Benzenesulfonamide,4-methoxy-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-

Modify Date: 2024-01-12 20:38:05

Benzenesulfonamide,4-methoxy-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]- Structure
Benzenesulfonamide,4-methoxy-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]- structure
Common Name Benzenesulfonamide,4-methoxy-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]-
CAS Number 3567-08-6 Molecular Weight 327.42200
Density 1.37g/cm3 Boiling Point 517.5ºC at 760mmHg
Molecular Formula C13H17N3O3S2 Melting Point N/A
MSDS N/A Flash Point 266.8ºC

 Names

Name Glysobuzole
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.37g/cm3
Boiling Point 517.5ºC at 760mmHg
Molecular Formula C13H17N3O3S2
Molecular Weight 327.42200
Flash Point 266.8ºC
Exact Mass 327.07100
PSA 117.80000
LogP 3.69980
Index of Refraction 1.589

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DB2780000
CHEMICAL NAME :
Benzenesulfonamide, N-(5-isobutyl-1,3,4-thiadiazol-2-yl)-p-methoxy-
CAS REGISTRY NUMBER :
3567-08-6
BEILSTEIN REFERENCE NO. :
0295174
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C13-H17-N3-O3-S2
MOLECULAR WEIGHT :
327.45
WISWESSER LINE NOTATION :
T5NN DSJ CMSWR DO1& E1Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
534 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,13,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
468 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,13,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia Endocrine - hypoglycemia Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 4,631,1962
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - muscle weakness Gastrointestinal - nausea or vomiting
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,13,1966 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
214 gm/kg/52W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - tumors
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,13,1966 *** REVIEWS *** TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970

 Safety Information

HS Code 2935009090

 Customs

HS Code 2935009090
Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

 Synonyms

4-methoxy-benzenesulfonic acid-(5-isobutyl-[1,3,4]thiadiazol-2-ylamide)
5-<4-Methoxy-benzolsulfonylamino>-2-isobutyl-1,3,4-thiadiazol
N-(5-isobutyl-[1,3,4]thiadiazol-2-yl)-4-methoxy-benzenesulfonamide
4-Methoxy-benzolsulfonsaeure-(5-isobutyl-[1,3,4]thiadiazol-2-ylamid)
Isobuzole
Wy-2340
Isopamin
5-<4-Methoxy-phenylsulfonylamino>-2-isobutyl-1,3,4-thiadiazol
SADA