(β,β-2H2)Tyrosine

Modify Date: 2024-01-10 15:37:59

(β,β-2H2)Tyrosine Structure
(β,β-2H2)Tyrosine structure
Common Name (β,β-2H2)Tyrosine
CAS Number 35693-18-6 Molecular Weight 183.20
Density 1.3±0.1 g/cm3 Boiling Point 385.2±32.0 °C at 760 mmHg
Molecular Formula C9H9D2NO3 Melting Point N/A
MSDS N/A Flash Point 186.7±25.1 °C

 Use of (β,β-2H2)Tyrosine


DL-Tyrosine-d2 is the deuterium labeled DL-Tyrosine. DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine)[1][2].

 Names

Name dl-4-hydroxyphenylalanine-3,3-d2
Synonym More Synonyms

 (β,β-2H2)Tyrosine Biological Activity

Description DL-Tyrosine-d2 is the deuterium labeled DL-Tyrosine. DL-Tyrosine is an aromatic nonessential amino acid synthesized from the essential amino acid phenylalanine. DL-Tyrosine is a precursor for several important neurotransmitters (epinephrine, norepinephrine, dopamine)[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. ClementeBretti, et al. Some thermodynamic properties of dl-Tyrosine and dl-Tryptophan. Effect of the ionic medium, ionic strength and temperature on the solubility and acid–base properties. Fluid Phase Equilibria.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 385.2±32.0 °C at 760 mmHg
Molecular Formula C9H9D2NO3
Molecular Weight 183.20
Flash Point 186.7±25.1 °C
Exact Mass 183.086441
PSA 83.55000
LogP 0.38
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.614
Storage condition -20C

 Synonyms

(β,β-H)Tyrosine
Tyrosine-β,β-d
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