propiomazine

Modify Date: 2024-01-08 18:50:27

propiomazine Structure
propiomazine structure
Common Name propiomazine
CAS Number 362-29-8 Molecular Weight 340.48200
Density 1.137g/cm3 Boiling Point 500.8ºC at 760mmHg
Molecular Formula C20H24N2OS Melting Point N/A
MSDS N/A Flash Point 256.7ºC

 Use of propiomazine


Propiomazine is an orally active antihistamine agent with sedative effects. Propiomazine can be used in the research of insomnia[1][2].

 Names

Name propiomazine
Synonym More Synonyms

 propiomazine Biological Activity

Description Propiomazine is an orally active antihistamine agent with sedative effects. Propiomazine can be used in the research of insomnia[1][2].
Related Catalog
In Vivo Propiomazine (0.2 mg/kg, nasal administration, rats) is quickly absorbed, followed by rapid reduction of the plasma concentrations[3]. Propiomazine (25 mg/kg, i.p., at 0 and 3 h after challenge) protects rats against CCl4-induced hepatic injury[4]. Propiomazine (0.31-20 mg/kg, i.v.) increases plasma prolactin concentrations in rats[5].

 Chemical & Physical Properties

Density 1.137g/cm3
Boiling Point 500.8ºC at 760mmHg
Molecular Formula C20H24N2OS
Molecular Weight 340.48200
Flash Point 256.7ºC
Exact Mass 340.16100
PSA 48.85000
LogP 4.89710

 Synthetic Route

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propiomazine Structure

propiomazine

CAS#:362-29-8

Literature: Bulletin de la Societe Chimique de France, , p. 1474,1480

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

Propiomazinum
1-[10-[2-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one
Propiomazinum [INN-Latin]
Propiomazina [INN-Spanish]
Wy-1359
Largon
Dorevan
Phenoctyl
1-[10-(2-dimethylamino-propyl)-10H-phenothiazin-2-yl]-propan-1-one
Propionylpromethazine
Propiomazina
1-[10-(2-dimethylamino-propyl)-phenothiazin-2-yl]-propan-1-one
10-<2-Dimethylamino-propyl>-3-propionyl-phenothiazin
3-Propionyl-10-<2-dimethylamino-propyl>-phenothiazin
1-[10-(2-Dimethylamino-propyl)-phenothiazin-2-yl]-propan-1-on
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