2-Dibenzofuranamine

Modify Date: 2025-09-12 12:59:05

2-Dibenzofuranamine Structure
2-Dibenzofuranamine structure
Common Name 2-Dibenzofuranamine
CAS Number 3693-22-9 Molecular Weight 183.20600
Density 1.283g/cm3 Boiling Point 369.1ºC at 760mmHg
Molecular Formula C12H9NO Melting Point 128°C
MSDS N/A Flash Point 177ºC

 Names

Name dibenzofuran-2-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.283g/cm3
Boiling Point 369.1ºC at 760mmHg
Melting Point 128°C
Molecular Formula C12H9NO
Molecular Weight 183.20600
Flash Point 177ºC
Exact Mass 183.06800
PSA 39.16000
LogP 3.74940
Index of Refraction 1.755

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HP4550000
CHEMICAL NAME :
2-Dibenzofuranamine
CAS REGISTRY NUMBER :
3693-22-9
BEILSTEIN REFERENCE NO. :
0142223
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C12-H9-N-O
MOLECULAR WEIGHT :
183.22
WISWESSER LINE NOTATION :
T B656 HOJ DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
168 mg/kg/90W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
22 gm/kg/52W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
80 mg/kg
REFERENCE :
BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 111,12P,1969 *** REVIEWS *** TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970

 Safety Information

HS Code 2932999099

 Synthetic Route

~73%

2-Dibenzofuranamine Structure

2-Dibenzofuranamine

CAS#:3693-22-9

Literature: Voss, Juergen; Waller, Edgar; Kraenke, Petra Advanced Synthesis and Catalysis, 1998 , vol. 340, # 5 p. 430 - 436

~%

2-Dibenzofuranamine Structure

2-Dibenzofuranamine

CAS#:3693-22-9

Literature: Gilman et al. Journal of the American Chemical Society, 1934 , vol. 56, p. 2473,2476 Full Text Show Details I.G. Farbenind. Patent: DE591213 , 1932 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 20, p. 436,437

~%

2-Dibenzofuranamine Structure

2-Dibenzofuranamine

CAS#:3693-22-9

Literature: UNIVERSAL DISPLAY CORPORATION Patent: US2011/204333 A1, 2011 ;

~%

2-Dibenzofuranamine Structure

2-Dibenzofuranamine

CAS#:3693-22-9

Literature: Voss, Juergen; Waller, Edgar; Kraenke, Petra Advanced Synthesis and Catalysis, 1998 , vol. 340, # 5 p. 430 - 436

~%

2-Dibenzofuranamine Structure

2-Dibenzofuranamine

CAS#:3693-22-9

Literature: Gilman; Avakian Journal of the American Chemical Society, 1945 , vol. 67, p. 349

~%

2-Dibenzofuranamine Structure

2-Dibenzofuranamine

CAS#:3693-22-9

Literature: Schimmelschmidt Justus Liebigs Annalen der Chemie, 1950 , vol. 566, p. 184,204

~%

2-Dibenzofuranamine Structure

2-Dibenzofuranamine

CAS#:3693-22-9

Literature: Schimmelschmidt Justus Liebigs Annalen der Chemie, 1950 , vol. 566, p. 184,204

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 2-DibenzofuranamineBioassay

View more

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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 Synonyms

Dibenzo[b,d]furan-2-amine
2-Aminodibenzofuran
2-aminobenzofuran
2-Ado
dibenzofuran-2-ylamine
2-Aminodiphenylene oxide
2-aminoodibenzofuran
2-DIBENZOFURANAMINE
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