2'-O-Succinyl-cAMP

Modify Date: 2026-08-08 08:47:08

2'-O-Succinyl-cAMP Structure
2'-O-Succinyl-cAMP structure
Common Name 2'-O-Succinyl-cAMP
CAS Number 36940-87-1 Molecular Weight 429.27900
Density 2.16g/cm3 Boiling Point 781.3ºC at 760mmHg
Molecular Formula C14H16N5O9P Melting Point N/A
MSDS USA Flash Point 426.3ºC

 Use of 2'-O-Succinyl-cAMP


2'-O-Succinyl-cAMP is a cAMP analog that can be covalently coupled to acetylcholinesterase. 2'-O-Succinyl-cAMP conjugate has been used as tracers in a classical heterogeneous competitive enzyme immunoassay allowing the determination of cAMP[1][2].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate
Synonym More Synonyms

 2'-O-Succinyl-cAMP Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description 2'-O-Succinyl-cAMP is a cAMP analog that can be covalently coupled to acetylcholinesterase. 2'-O-Succinyl-cAMP conjugate has been used as tracers in a classical heterogeneous competitive enzyme immunoassay allowing the determination of cAMP[1][2].
Related Catalog
References

[1]. Pradelles P, et, al. Enzyme immunoassays of adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate using acetylcholinesterase. Anal Chem. 1989 Mar 1;61(5):447-53.

[2]. Luttrell BM, et, al. Reaction coupling of chelation and antigen binding in the calcium ion-dependent antibody binding of cyclic AMP. J Biol Chem. 1991 Nov 15;266(32):21626-30.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 2.16g/cm3
Boiling Point 781.3ºC at 760mmHg
Molecular Formula C14H16N5O9P
Molecular Weight 429.27900
Flash Point 426.3ºC
Exact Mass 429.06900
PSA 208.02000
LogP 0.17950
Index of Refraction 1.849
InChIKey QNPSLGPIZRJDAN-UISLRAPISA-N
SMILES Nc1ncnc2c1ncn2C1OC2COP(=O)(O)OC2C1OC(=O)CCC(=O)O

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles6

More Articles

This table lists relevant public references with title, journal and publication metadata for this compound.

Functional roles of protein kinase A (PKA) and exchange protein directly activated by 3',5'-cyclic adenosine 5'-monophosphate (cAMP) 2 (EPAC2) in cAMP-mediated actions in adrenocortical cells.

Endocrinology 151 , 2151-2161, (2010)

In the adrenal cortex, the biosynthesis of steroid hormones is controlled by the pituitary-derived hormone ACTH. The functions of ACTH are principally relayed by activating cAMP-dependent signaling pa...

Different role of cAMP dependent protein kinase and CaMKII in H3 receptor regulation of histamine synthesis and release

Neuroscience 164 , 1244-1251, (2009)

Histamine H3 autoreceptors induce a negative feedback on histamine synthesis and release. While it is known that cAMP/cAMP dependent protein kinase (PKA) and Ca2+/CaMKII transduction pathways mediate ...

A real-time fluorescent assay of the purified nitric oxide receptor, guanylyl cyclase.

Anal. Biochem. 402 , 129-136, (2010)

Nitric oxide (NO) mediates intercellular signaling through activation of its receptor, soluble guanylyl cyclase (sGC), leading to elevation of intracellular guanosine 3',5'-cyclic monophosphate (cGMP)...

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Adenosine 3',5'-phosphoric acid 2'-hydrogen butanedioate
2'-O-MONOSUCCINYLADENOSINE 3':5'-*CYCLIC MONOPHOSPH
succinyladenosine 3',5'-cyclic monophosphate

 2'-O-Succinyl-cAMP | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the CAS number of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate?
A: CAS number of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate is 36940-87-1.
Q: What is the English name of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate?
A: The English name of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate is 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate.
Q: What is the molecular weight of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate?
A: Molecular weight of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate is 429.27900.
Q: What is the LogP of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate?
A: LogP of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate is 0.17950.
Q: What is the boiling point of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate?
A: Boiling point of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate is 781.3ºC at 760mmHg.
Q: What are the uses of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate?
A: Main uses of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate: 2'-O-Succinyl-cAMP is a cAMP analog that can be covalently coupled to acetylcholinesterase. 2'-O-Succinyl-cAMP conjugate has been used as tracers in a classical heterogeneous competitive enzyme immunoassay allowing the determination of cAMP[1][2].
Q: What is the molecular formula of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate?
A: Molecular formula of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate is C14H16N5O9P.
Q: What is the SMILES notation of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate?
A: SMILES notation of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate is Nc1ncnc2c1ncn2C1OC2COP(=O)(O)OC2C1OC(=O)CCC(=O)O.
Q: What is the polar surface area (PSA) of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate?
A: Polar surface area (PSA) of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate is 208.02000.
Q: What English synonyms does 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate have?
A: English synonyms of 2'-o-monosuccinyladenosine 3':5'-cyclic monophosphate: Adenosine 3',5'-phosphoric acid 2'-hydrogen butanedioate, 2'-O-MONOSUCCINYLADENOSINE 3':5'-*CYCLIC MONOPHOSPH, succinyladenosine 3',5'-cyclic monophosphate.

 2'-O-Succinyl-cAMPfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
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