AF/AETP

Modify Date: 2024-01-14 19:21:35

AF/AETP Structure
AF/AETP structure
Common Name AF/AETP
CAS Number 37392-57-7 Molecular Weight 836.967
Density 1.3±0.1 g/cm3 Boiling Point N/A
Molecular Formula C44H60N4O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name (9E,26E)-26-{[(4-Ethyl-1-piperazinyl)amino]methylene}-2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23,27-trioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29)-heptaen-13-yl acetate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Molecular Formula C44H60N4O12
Molecular Weight 836.967
Exact Mass 836.420776
PSA 220.15000
LogP 3.44
Index of Refraction 1.626

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KD1920300
CHEMICAL NAME :
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy -8-((4-ethyl1-piperaz inylimino)methyl)-, 21-acetate
CAS REGISTRY NUMBER :
37392-57-7
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C44-H60-N4-O12
MOLECULAR WEIGHT :
837.08

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1270 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,531,1977

 Synthetic Route

~%

AF/AETP Structure

AF/AETP

CAS#:37392-57-7

Literature: Cricchio; Arioli; Lancini Farmaco, Edizione Scientifica, 1975 , vol. 30, # 8 p. 605 - 619

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

2,7-(Epoxy[1,11,13]pentadecatrienoimino)naphtho[2,1-b]furan-1,9,11(2H,8H)-trione, 21-(acetyloxy)-8-[[(4-ethyl-1-piperazinyl)amino]methylene]-5,6,17,19-tetrahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-, (8E,24E)-
(9E,26E)-26-{[(4-Ethyl-1-piperazinyl)amino]methylene}-2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23,27-trioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1.0]triaconta-1(28)
 ,2,4,9,19,21,25(29)-heptaen-13-yl acetate