3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride

Modify Date: 2026-09-21 01:21:37

3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride Structure
3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride structure
Common Name 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride
CAS Number 37781-33-2 Molecular Weight 262.56300
Density 1.309g/cm3 Boiling Point 323.4ºC at 760 mmHg
Molecular Formula C11H10Cl3N Melting Point N/A
MSDS N/A Flash Point 179ºC

Summary: 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride (CAS号:37781-33-2), molecular formula C11H10Cl3N, molecular weight 262.56300, for research-use only, not for medical or clinical usage.


 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.309g/cm3
Boiling Point 323.4ºC at 760 mmHg
Molecular Formula C11H10Cl3N
Molecular Weight 262.56300
Flash Point 179ºC
Exact Mass 260.98800
PSA 12.89000
LogP 4.73740
Index of Refraction 1.632
InChIKey GPLQWAVBVGCDBW-UHFFFAOYSA-N
SMILES Cc1c(Cl)c(CCl)nc2ccccc12.Cl

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 3-Chloro-2-(chloromethyl)-4-methylquinoline, HCl
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:3-Chloro-2-(chloromethyl)-4-methylquinoline, HCl
CAS number:37781-33-2

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C11H9Cl2N.ClH
Molecular weight:262.6

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

HS Code 2933499090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~75%

3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride Structure

3-Chloro-2-(chl...

CAS#:37781-33-2

Learn More
Literature: Ryabukhin, Sergey V.; Naumchik, Vasiliy S.; Plaskon, Andrey S.; Grygorenko, Oleksandr O.; Tolmachev, Andrey A. Journal of Organic Chemistry, 2011 , vol. 76, # 14 p. 5774 - 5781

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  2

DownStream  0

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

3-chloro-2-(chloromethyl)-4-methylquinoline,hydrochloride

  | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the English name of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride?
A: The English name of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride is 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride.
Q: What is the InChIKey of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride?
A: InChIKey of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride is GPLQWAVBVGCDBW-UHFFFAOYSA-N.
Q: What is the molecular weight of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride?
A: Molecular weight of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride is 262.56300.
Q: What is the boiling point of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride?
A: Boiling point of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride is 323.4ºC at 760 mmHg.
Q: What English synonyms does 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride have?
A: English synonyms of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride: 3-chloro-2-(chloromethyl)-4-methylquinoline,hydrochloride.
Q: What is the polar surface area (PSA) of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride?
A: Polar surface area (PSA) of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride is 12.89000.
Q: What are the upstream materials of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride?
A: Related upstream materials(CAS) of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride: 551-93-9;534-07-6.
Q: What is the SMILES notation of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride?
A: SMILES notation of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride is Cc1c(Cl)c(CCl)nc2ccccc12.Cl.
Q: What is the molecular formula of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride?
A: Molecular formula of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride is C11H10Cl3N.
Q: What is the LogP of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride?
A: LogP of 3-Chloro-2-(chloromethyl)-4-methylquinoline hydrochloride is 4.73740.

 factory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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