N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine
Modify Date: 2026-07-15 17:56:20
![N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine Structure](https://www.chemsrc.com/extcaspic/213/379230-68-9.png)
N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine structure
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Common Name | N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine | ||
|---|---|---|---|---|
| CAS Number | 379230-68-9 | Molecular Weight | 428.9 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H25ClN4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine |
|---|
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C22H25ClN4O3 |
|---|---|
| Molecular Weight | 428.9 |
| InChIKey | UDMCXVWGJLMNDD-UHFFFAOYSA-N |
| SMILES | COc1ccc(Cl)c(Nc2ncnc3cc(OC)cc(OC4CCN(C)CC4)c23)c1 |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Inhibition of KDR
Source: ChEMBL
Target: Vascular endothelial growth factor receptor 2
External Id: CHEMBL855514
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Name: Antiproliferative activity against mouse NIH3T3 cell line transfected with c-SRC
Source: ChEMBL
Target: Proto-oncogene tyrosine-protein kinase Src
External Id: CHEMBL855536
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Name: Inhibition of A549 cell migration by microdroplet migration assay
Source: ChEMBL
Target: A549
External Id: CHEMBL854953
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Name: Selectivity for c-SRC over KDR
Source: ChEMBL
Target: VEGF-receptor 2 and tyrosine-protein kinase SRC
External Id: CHEMBL907217
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Name: In Vitro Src Kinase Inhibition Test from Article 10.1021/jm060434q: "N-(5-chloro-1,3-...
Source: BindingDB
Target: N/A
External Id: BindingDB_1572_1
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Name: Inhibition of human c-Src in NIH3T3 cells
Source: ChEMBL
Target: Proto-oncogene tyrosine-protein kinase Src
External Id: CHEMBL855513
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Name: ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake fl...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3301363
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This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the English name of N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine? |
| A: The English name of N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine is N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine. |
| Q: What is the InChIKey of N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine? |
| A: InChIKey of N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine is UDMCXVWGJLMNDD-UHFFFAOYSA-N. |
| Q: What is the CAS number of N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine? |
| A: CAS number of N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine is 379230-68-9. |
| Q: What is the SMILES notation of N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine? |
| A: SMILES notation of N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine is COc1ccc(Cl)c(Nc2ncnc3cc(OC)cc(OC4CCN(C)CC4)c23)c1. |
| Q: What is the molecular weight of N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine? |
| A: Molecular weight of N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine is 428.9. |
| Q: What is the Chinese name of 379230-68-9? |
| A: Chinese name of 379230-68-9 is 379230-68-9. |
| Q: What is the molecular formula of N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine? |
| A: Molecular formula of N-(2-chloro-5-methoxyphenyl)-7-methoxy-5-[(1-methylpiperidin-4-yl)oxy]quinazolin-4-amine is C22H25ClN4O3. |