GW297361
Modify Date: 2024-01-23 10:27:10
GW297361 structure
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Common Name | GW297361 | ||
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| CAS Number | 388627-21-2 | Molecular Weight | 372.42 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H12N4O3S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GW297361GW297361 is an oxindole CDK inhibitor that elicits a Pho85-selective response in cells. GW297361 inhibits yeast Cdk1 and Pho85 with IC50s of 20 nM and 400 nM in vitro, respectively[1]. |
| Name | GW297361 |
|---|
| Description | GW297361 is an oxindole CDK inhibitor that elicits a Pho85-selective response in cells. GW297361 inhibits yeast Cdk1 and Pho85 with IC50s of 20 nM and 400 nM in vitro, respectively[1]. |
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| Related Catalog | |
| Target |
yeast Cdk1:20 nM (IC50) yeast Pho85:400 nM (IC50) human CDK2:1.9 nM (IC50) human CDK9:10 nM (IC50) human CDK1:30 nM (IC50) human CDK4:300 nM (IC50) VEGFR2:120 nM (IC50) SRC:930 nM (IC50) |
| In Vitro | GW297361 (20 μM; 15 min) 部分抑制细胞内的 Cdk1[1]。 Western Blot Analysis[1] Cell Line: YRP1 cells Concentration: 20 μM Incubation Time: 20 μM Result: An intermediate level of the Orc6 was converted to the faster-migrating isoform (lower:upper = 2:1). |
| References |
| Molecular Formula | C16H12N4O3S2 |
|---|---|
| Molecular Weight | 372.42 |