ATV399
Modify Date: 2024-04-11 18:45:34
ATV399 structure
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Common Name | ATV399 | ||
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| CAS Number | 393834-37-2 | Molecular Weight | 465.522 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C24H23N3O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ATV399ATV399 (ATV-399) is a novel small molecule that dose-dependently reduces the cleaved caspase9 levels with IC50 of 3.3 uM, inhibits dimerization of iNOS; inhibits cleaved caspase-9 activation and subsequent β-cell apoptosis induced by a combination of IL-1β, IFN-γ and high glucose. |
| Name | N-(4-{[2-(3-Pyridinyl)-1-piperidinyl]sulfonyl}phenyl)-1,3-benzodioxole-5-carboxamide |
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| Synonym | More Synonyms |
| Description | ATV399 (ATV-399) is a novel small molecule that dose-dependently reduces the cleaved caspase9 levels with IC50 of 3.3 uM, inhibits dimerization of iNOS; inhibits cleaved caspase-9 activation and subsequent β-cell apoptosis induced by a combination of IL-1β, IFN-γ and high glucose. |
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| References | References 1. Zhong L, et al. Br J Pharmacol. 2018 Jun 11. doi: 10.1111/bph.14388. View Related Products by Target Nitric Oxide Synthase (NOS) |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C24H23N3O5S |
| Molecular Weight | 465.522 |
| Exact Mass | 465.135834 |
| LogP | 3.00 |
| Index of Refraction | 1.657 |
| 1,3-Benzodioxole-5-carboxamide, N-[4-[[2-(3-pyridinyl)-1-piperidinyl]sulfonyl]phenyl]- |
| N-(4-{[2-(3-Pyridinyl)-1-piperidinyl]sulfonyl}phenyl)-1,3-benzodioxole-5-carboxamide |