N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE

Modify Date: 2024-01-02 19:54:26

N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE Structure
N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE structure
Common Name N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE
CAS Number 39837-08-6 Molecular Weight 187.25900
Density N/A Boiling Point N/A
Molecular Formula C8H13NO2S Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE


N-Butyryl-DL-homocysteine thiolactone is an N-acyl homoserine lactone (AHL) analogue. N-Butyryl-DL-homocysteine thiolactone shows potential adverse effect and toxicity on bacteria. AHLs are potent inhibitors of biofilm formation and virulence factors, and has been used for degrading microbial communities, reducing bacterial pathogenicity[1][2].

 Names

Name N-(2-oxothiolan-3-yl)butanamide
Synonym More Synonyms

 N-BUTYRYL-DL-HOMOCYSTEINE THIOLACTONE Biological Activity

Description N-Butyryl-DL-homocysteine thiolactone is an N-acyl homoserine lactone (AHL) analogue. N-Butyryl-DL-homocysteine thiolactone shows potential adverse effect and toxicity on bacteria. AHLs are potent inhibitors of biofilm formation and virulence factors, and has been used for degrading microbial communities, reducing bacterial pathogenicity[1][2].
Related Catalog
References

[1]. Khalilzadeh P, et al. Growth inhibition of adherent Pseudomonas aeruginosa by an N-butanoyl-L-homoserine lactone analog. Can J Microbiol. 2010 Apr;56(4):317-25.

[2]. Iyer R, et al. Synthetic analogs of bacterial quorum sensors: US, US20110053890[P]. 2011-03-03.

 Chemical & Physical Properties

Molecular Formula C8H13NO2S
Molecular Weight 187.25900
Exact Mass 187.06700
PSA 74.96000
LogP 1.77510

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR UN 3335
HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles5

More Articles
Anticonvulsive effect of folic acid in homocysteine thiolactone-induced seizures.

Cell. Mol. Neurobiol. 31 , 1221-1228, (2011)

Numerous studies have linked folate deficiency and resultant elevated plasma homocysteine levels with an increased risk of neurodegenerative diseases and seizures. The aim of the present study was to ...

Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones.

Microbiology 143 , 3703, (1997)

Quorum sensing relies upon the interaction of a diffusible signal molecule with a transcriptional activator protein to couple gene expression with cell population density. In Gram-negative bacteria, s...

[Effect of thiolactone homocysteine loading on adenosine metabolism in rats: relationship with platelet hyper-reactivity, correction of this metabolism disorders by vitamin-microelement complex].

Ukr. Biokhim. Zh. 82 , 59-66, (2010)

Influence of DL-homocysteine thiolactone loading (100 mg/kg by intragastric administration for 28 days) on enzymes activity of adenylic nucleotide and adenosine metabolism in the blood serum, platelet...

 Synonyms

N-Butyryl-DL-homocysteine thiolactone
N-butyryl-L-Homocysteine thiolactone
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