kievitone
Modify Date: 2024-01-06 21:18:54
kievitone structure
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Common Name | kievitone | ||
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| CAS Number | 40105-60-0 | Molecular Weight | 356.36900 | |
| Density | 1.384g/cm3 | Boiling Point | 639.6ºC at 760 mmHg | |
| Molecular Formula | C20H20O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 231.4ºC | |
Use of kievitoneKievitone, an isoflavanone, could be isolated from hypocotyls of Phaseolus vulgaris L. infected with Rhizoctonia solani Kühn. Kievitone has antifungal activity and antitumor activity[1][2]. |
| Name | kievitone |
|---|---|
| Synonym | More Synonyms |
| Description | Kievitone, an isoflavanone, could be isolated from hypocotyls of Phaseolus vulgaris L. infected with Rhizoctonia solani Kühn. Kievitone has antifungal activity and antitumor activity[1][2]. |
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| Related Catalog | |
| In Vitro | Kievitone (0-40 μM; 4 天) 抑制雌激素受体 (ER) 阳性乳腺癌细胞株 MCF-7 和 T47D 以及 ER 阴性乳腺癌细胞株 SKBR3 的增殖 (IC50 值 为 5-18 μM)[2]。 Kievitone (0-40 μM; 48 h) 抑制由胰岛素样生长因子 1、胰岛素样生长因子 2、碱性成纤维细胞生长因子或转化生长因子 α 刺激的 MCF-7 细胞的 DNA 合成[2]。 Cell Viability Assay[2] Cell Line: MCF-7, T47D and SKBR3 cells Concentration: 0-40 μM Incubation Time: 4 days Result: Inhibited breast cancer cell proliferation in a dose-dependent manner. |
| References |
| Density | 1.384g/cm3 |
|---|---|
| Boiling Point | 639.6ºC at 760 mmHg |
| Molecular Formula | C20H20O6 |
| Molecular Weight | 356.36900 |
| Flash Point | 231.4ºC |
| Exact Mass | 356.12600 |
| PSA | 107.22000 |
| LogP | 3.37660 |
| Index of Refraction | 1.663 |
| 3-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one |
| 3-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen-4-one |
| Kievitone |