8CN

Modify Date: 2024-01-07 11:37:09

8CN structure	Common Name	8CN
	CAS Number	40106-14-7	Molecular Weight	206.31
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₄N₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 8CN

8CN, a 2-amino-thiophene derivative, has anti-leishmanial activity. 8CN can be used in research of Leishmaniasis[1].

Name	2-Amino-4,5,6,7,8,9-hexahydrocycloocta-[b]thiophene-3-carbonitrile

Description	8CN, a 2-amino-thiophene derivative, has anti-leishmanial activity. 8CN can be used in research of Leishmaniasis[1].
Related Catalog	Research Areas >> Infection
In Vitro	8CN (72 h) 对亚马逊利什曼原虫的两种进化形式(无鞭毛体和前鞭毛体)具有抗利什曼病活性，IC50 值分别为 9.8 和 1.2 μM[1]。
References	[1]. Luna IS, et, al. Computer-Aided drug design of new 2-amino-thiophene derivatives as anti-leishmanial agents. Eur J Med Chem. 2023 Mar 15;250:115223.

Molecular Formula	C₁₁H₁₄N₂S
Molecular Weight	206.31
Exact Mass	206.08800
PSA	78.05000
LogP	3.44218

HS Code	2934999090

Cyclooctanone structure

Cyclooctanone

CAS#:502-49-8

Malononitrile structure

Malononitrile

CAS#:109-77-3

~87%

8CN Structure

8CN

CAS#:40106-14-7

Literature: Arhin, Francis; Belanger, Odette; Ciblat, Stephane; Dehbi, Mohammed; Delorme, Daniel; Dietrich, Evelyne; Dixit, Dilip; Lafontaine, Yanick; Lehoux, Dario; Liu, Jing; McKay, Geoffrey A.; Moeck, Greg; Reddy, Ranga; Rose, Yannick; Srikumar, Ramakrishnan; Tanaka, Kelly S.E.; Williams, Daniel M.; Gros, Philippe; Pelletier, Jerry; Parr Jr., Thomas R.; Far, Adel Rafai Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 17 p. 5812 - 5832

Precursor 2
CAS#:502-49-8 Cyclooctanone CAS#:109-77-3 Malononitrile
DownStream 1
CAS#:40106-15-8 2-amino-4,5,6,7...

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 2-amino-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carbonitrile
Price: Check
Purity: 95.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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