6-(2,2,2-trifluoroacetyl)spiro[7,8-dihydro-5H-[1,3]dioxolo[4,5-h][2]benzazepine-9,4'-cyclohexa-2,5-diene]-1'-one
![6-(2,2,2-trifluoroacetyl)spiro[7,8-dihydro-5H-[1,3]dioxolo[4,5-h][2]benzazepine-9,4'-cyclohexa-2,5-diene]-1'-one Structure](https://image.chemsrc.com/caspic/370/40135-91-9.png)
6-(2,2,2-trifluoroacetyl)spiro[7,8-dihydro-5H-[1,3]dioxolo[4,5-h][2]benzazepine-9,4'-cyclohexa-2,5-diene]-1'-one structure
|
Common Name | 6-(2,2,2-trifluoroacetyl)spiro[7,8-dihydro-5H-[1,3]dioxolo[4,5-h][2]benzazepine-9,4'-cyclohexa-2,5-diene]-1'-one | ||
|---|---|---|---|---|
| CAS Number | 40135-91-9 | Molecular Weight | 365.30300 | |
| Density | 1.49g/cm3 | Boiling Point | 554.5ºC at 760 mmHg | |
| Molecular Formula | C18H14F3NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 289.2ºC | |
| Name | 6-(2,2,2-trifluoroacetyl)spiro[7,8-dihydro-5H-[1,3]dioxolo[4,5-h][2]benzazepine-9,4'-cyclohexa-2,5-diene]-1'-one |
|---|
| Density | 1.49g/cm3 |
|---|---|
| Boiling Point | 554.5ºC at 760 mmHg |
| Molecular Formula | C18H14F3NO4 |
| Molecular Weight | 365.30300 |
| Flash Point | 289.2ºC |
| Exact Mass | 365.08700 |
| PSA | 55.84000 |
| LogP | 2.58070 |
| Index of Refraction | 1.604 |
| InChIKey | HAWKFAPZXUJREV-UHFFFAOYSA-N |
| SMILES | O=C1C=CC2(C=C1)CCN(C(=O)C(F)(F)F)Cc1cc3c(cc12)OCO3 |
|
~81%
6-(2,2,2-triflu... CAS#:40135-91-9 |
| Literature: Dohi, Toshifumi; Minamitsuji, Yutaka; Maruyama, Akinobu; Hirose, Satoshi; Kita, Yasuyuki Organic Letters, 2008 , vol. 10, # 16 p. 3559 - 3562 |
|
~64%
6-(2,2,2-triflu... CAS#:40135-91-9 |
| Literature: Murase, Masayuki; Kotani, Eiichi; Okazaki, Kousuke; Tobinaga, Seisho Chemical & Pharmaceutical Bulletin, 1986 , vol. 34, # 8 p. 3159 - 3165 |
|
~%
6-(2,2,2-triflu... CAS#:40135-91-9 |
| Literature: Kita, Yasuyuki; Arisawa, Mitsuhiro; Gyoten, Michiyo; Nakajima, Makiko; Hamada, Ryuji; Tohma, Hirofumi; Takada, Takeshi Journal of Organic Chemistry, 1998 , vol. 63, # 19 p. 6625 - 6633 |
|
~%
6-(2,2,2-triflu... CAS#:40135-91-9 |
| Literature: Kita, Yasuyuki; Arisawa, Mitsuhiro; Gyoten, Michiyo; Nakajima, Makiko; Hamada, Ryuji; Tohma, Hirofumi; Takada, Takeshi Journal of Organic Chemistry, 1998 , vol. 63, # 19 p. 6625 - 6633 |
|
~%
6-(2,2,2-triflu... CAS#:40135-91-9 |
| Literature: Kita, Yasuyuki; Arisawa, Mitsuhiro; Gyoten, Michiyo; Nakajima, Makiko; Hamada, Ryuji; Tohma, Hirofumi; Takada, Takeshi Journal of Organic Chemistry, 1998 , vol. 63, # 19 p. 6625 - 6633 |
|
~%
6-(2,2,2-triflu... CAS#:40135-91-9 |
| Literature: Kodama, Sumiaki; Takita, Hirofumi; Kajimoto, Tetsuya; Nishide, Kiyoharu; Node, Manabu Tetrahedron, 2004 , vol. 60, # 22 p. 4901 - 4907 |
|
~%
6-(2,2,2-triflu... CAS#:40135-91-9 |
| Literature: Kodama, Sumiaki; Takita, Hirofumi; Kajimoto, Tetsuya; Nishide, Kiyoharu; Node, Manabu Tetrahedron, 2004 , vol. 60, # 22 p. 4901 - 4907 |
![Acetamide,N-(1,3-benzodioxol-5-ylmethyl)-2,2,2-trifluoro-N-[2-(4-hydroxyphenyl)ethyl] structure](https://image.chemsrc.com/caspic/301/40135-88-4.png)
![4-[2-[(6-bromobenzo[1,3]dioxol-5-yl)methylamino]ethyl]phenol structure](https://image.chemsrc.com/caspic/140/34315-37-2.png)
|
Name: Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3856991
|
|
Name: Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL3856992
|