tert-butyl 4-(5-bromo-2,3-dihydroindol-1-yl)piperidine-1-carboxylate

Modify Date: 2024-01-09 05:49:35

tert-butyl 4-(5-bromo-2,3-dihydroindol-1-yl)piperidine-1-carboxylate structure	Common Name	tert-butyl 4-(5-bromo-2,3-dihydroindol-1-yl)piperidine-1-carboxylate
	CAS Number	401565-86-4	Molecular Weight	381.30700
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₂₅BrN₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Name	tert-butyl 4-(5-bromo-2,3-dihydroindol-1-yl)piperidine-1-carboxylate
Synonym	More Synonyms

Molecular Formula	C₁₈H₂₅BrN₂O₂
Molecular Weight	381.30700
Exact Mass	380.11000
PSA	32.78000
LogP	4.21400

tert-butyl 4-(indolin-1-yl)piperidine-1-carboxylate structure

tert-butyl 4-(i...

CAS#:400828-91-3

~10%

tert-butyl 4-(5-bromo-2,3-dihydroindol-1-yl)piperidine-1-carboxylate Structure

tert-butyl 4-(5...

CAS#:401565-86-4

Literature: Annedi, Subhash C.; Maddaford, Shawn P.; Ramnauth, Jailall; Renton, Paul; Rybak, Taras; Silverman, Sarah; Rakhit, Suman; Mladenova, Gabriela; Dove, Peter; Andrews, John S.; Zhang, Dongqin; Porreca, Frank European Journal of Medicinal Chemistry, 2012 , vol. 55, p. 94 - 107,14 Title/Abstract Full Text Show Details Annedi, Subhash C.; Maddaford, Shawn P.; Ramnauth, Jailall; Renton, Paul; Rybak, Taras; Silverman, Sarah; Rakhit, Suman; Mladenova, Gabriela; Dove, Peter; Andrews, John S.; Zhang, Dongqin; Porreca, Frank European Journal of Medicinal Chemistry, 2012 , vol. 55, p. 94 - 107

5-Bromoindoline structure

5-Bromoindoline

CAS#:22190-33-6

N-(tert-Butoxycarbonyl)-4-piperidone structure

N-(tert-Butoxyc...

CAS#:79099-07-3

~90%

tert-butyl 4-(5-bromo-2,3-dihydroindol-1-yl)piperidine-1-carboxylate Structure

tert-butyl 4-(5...

CAS#:401565-86-4

Literature: GLAXO GROUP LIMITED Patent: WO2006/38006 A2, 2006 ; Location in patent: Page/Page column 16-17 ; WO 2006/038006 A2

Indoline structure

Indoline

CAS#:496-15-1

~%

tert-butyl 4-(5-bromo-2,3-dihydroindol-1-yl)piperidine-1-carboxylate Structure

tert-butyl 4-(5...

CAS#:401565-86-4

Literature: Annedi, Subhash C.; Maddaford, Shawn P.; Ramnauth, Jailall; Renton, Paul; Rybak, Taras; Silverman, Sarah; Rakhit, Suman; Mladenova, Gabriela; Dove, Peter; Andrews, John S.; Zhang, Dongqin; Porreca, Frank European Journal of Medicinal Chemistry, 2012 , vol. 55, p. 94 - 107,14 Title/Abstract Full Text Show Details Annedi, Subhash C.; Maddaford, Shawn P.; Ramnauth, Jailall; Renton, Paul; Rybak, Taras; Silverman, Sarah; Rakhit, Suman; Mladenova, Gabriela; Dove, Peter; Andrews, John S.; Zhang, Dongqin; Porreca, Frank European Journal of Medicinal Chemistry, 2012 , vol. 55, p. 94 - 107

N-(tert-Butoxycarbonyl)-4-piperidone structure

N-(tert-Butoxyc...

CAS#:79099-07-3

~%

tert-butyl 4-(5-bromo-2,3-dihydroindol-1-yl)piperidine-1-carboxylate Structure

tert-butyl 4-(5...

CAS#:401565-86-4

Literature: Annedi, Subhash C.; Maddaford, Shawn P.; Ramnauth, Jailall; Renton, Paul; Rybak, Taras; Silverman, Sarah; Rakhit, Suman; Mladenova, Gabriela; Dove, Peter; Andrews, John S.; Zhang, Dongqin; Porreca, Frank European Journal of Medicinal Chemistry, 2012 , vol. 55, p. 94 - 107,14 Title/Abstract Full Text Show Details Annedi, Subhash C.; Maddaford, Shawn P.; Ramnauth, Jailall; Renton, Paul; Rybak, Taras; Silverman, Sarah; Rakhit, Suman; Mladenova, Gabriela; Dove, Peter; Andrews, John S.; Zhang, Dongqin; Porreca, Frank European Journal of Medicinal Chemistry, 2012 , vol. 55, p. 94 - 107

Precursor 4
CAS#:400828-91-3 tert-butyl 4-(i... CAS#:22190-33-6 5-Bromoindoline CAS#:79099-07-3 N-(tert-Butoxyc... CAS#:496-15-1 Indoline
DownStream 0

1-Piperidinecarboxylicacid,4-(5-bromo-2,3-dihydro-1H-indol-1-yl)-,1,1-dimethylethyl ester

tert-butyl 4-(5-bromoindolin-1-yl)piperidine-1-carboxylate

1,1-dimethylethyl 4-(5-bromo-2,3-dihydro-1H-indol-1-yl)-1-piperidinecarboxylate

TERT-BUTYL 4-(5-BROMO-2,3-DIHYDRO-1H-INDOL-1-YL)PIPERIDINE-1-CARBOXYLATE

Dichloromethane
CAS#:75-09-2

Polyacrylic acid
CAS#:9003-01-4

sodium carbonate
CAS#:497-19-8

Silicon dioxide
CAS#:7631-86-9

Triethanolamine
CAS#:102-71-6

Demeton
CAS#:126-75-0

Water
CAS#:7732-18-5

4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9

Diclofenac sodium
CAS#:15307-79-6

Budesonide
CAS#:51372-29-3