4-methylbenzo[c]phenanthrene

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C19-H14

MOLECULAR WEIGHT :

242.33

WISWESSER LINE NOTATION :

L C6 B666J G1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

14 gm/kg/71W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

REFERENCE :

PRLBA4 Proceedings of the Royal Society of London, Series B: Biological Sciences. (Royal Soc., 6 Carlton House Terrace, London SW1Y 5AG, UK) V.76- 1905- Volume(issue)/page/year: 129,439,1940

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Administration onto the skin

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

1460 mg/kg/61W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

REFERENCE :

PRLBA4 Proceedings of the Royal Society of London, Series B: Biological Sciences. (Royal Soc., 6 Carlton House Terrace, London SW1Y 5AG, UK) V.76- 1905- Volume(issue)/page/year: 129,439,1940

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

4600 mg/kg/68W-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors

REFERENCE :

PRLBA4 Proceedings of the Royal Society of London, Series B: Biological Sciences. (Royal Soc., 6 Carlton House Terrace, London SW1Y 5AG, UK) V.76- 1905- Volume(issue)/page/year: 129,439,1940