NF(N-Me)GA(N-Me)IL

Modify Date: 2024-01-20 12:04:14

NF(N-Me)GA(N-Me)IL Structure
NF(N-Me)GA(N-Me)IL structure
Common Name NF(N-Me)GA(N-Me)IL
CAS Number 409085-42-3 Molecular Weight 661.79
Density N/A Boiling Point N/A
Molecular Formula C32H51N7O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NF(N-Me)GA(N-Me)IL


NF(N-Me)GA(N-Me)IL is a biological active peptide. (This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.)

 Names

Name NF(N-Me)GA(N-Me)IL

 NF(N-Me)GA(N-Me)IL Biological Activity

Description NF(N-Me)GA(N-Me)IL is a biological active peptide. (This amino acids 22 to 27 fragment is a modification of the human islet amyloid polypeptide hIAPP (NFGAIL) with N-methylation of the amide bonds at G24 and I26. The introduction of two N-methyl rests in the amyloid-core-containing sequence NFGAIL converts this amyloidogenic and cytotoxic sequence into non-amyloidogenic and non-cytotoxic peptide. The peptide is able to bind with high-affinity full-length hIAPP and to inhibit its fibrillogenesis.)
Related Catalog

 Chemical & Physical Properties

Molecular Formula C32H51N7O8
Molecular Weight 661.79