Mitragynine

Modify Date: 2024-01-02 20:49:23

Mitragynine Structure
Mitragynine structure
Common Name Mitragynine
CAS Number 4098-40-2 Molecular Weight 398.495
Density 1.2±0.1 g/cm3 Boiling Point 560.3±50.0 °C at 760 mmHg
Molecular Formula C29H33N5O11 Melting Point 92-95ºC
MSDS N/A Flash Point 292.7±30.1 °C
Symbol GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
Signal Word Danger

 Use of Mitragynine


Mitragynine is an indole alkaloid from the plant Mitragyna speciosa. It has stimulatory, antinociceptive, and opiate-like effects, acting through noradrenergic, serotonergic, and opioid receptors.1,2 Mitragynine has a higher affinity for the μ-opioid rece

 Names

Name Mitragynine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 560.3±50.0 °C at 760 mmHg
Melting Point 92-95ºC
Molecular Formula C29H33N5O11
Molecular Weight 398.495
Flash Point 292.7±30.1 °C
Exact Mass 398.220551
PSA 221.48000
LogP 3.88
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.605

 Safety Information

Symbol GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
Signal Word Danger
Hazard Statements H225-H301 + H311 + H331-H370
Precautionary Statements P210-P260-P280-P301 + P310-P311
Hazard Codes F,T
Risk Phrases 11-23/24/25-39/23/24/25-36/37/38-22
Safety Phrases 7-16-36/37-45-26
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
HS Code 29339900

 Synthetic Route

 Precursor & DownStream

Precursor  1

DownStream  1

 Articles26

More Articles
A drug fatality involving Kratom.

J. Forensic Sci. 58 Suppl 1 , S278-9, (2013)

A 17-year-old white man who showed no obvious signs of trauma was found unresponsive in bed and was pronounced dead at the scene. The decedent had a documented history of heroin abuse and chronic back...

Orally active opioid compounds from a non-poppy source.

J. Med. Chem. 56(12) , 4840-8, (2013)

The basic science and clinical use of morphine and other "opioid" drugs are based almost exclusively on the extracts or analogues of compounds isolated from a single source, the opium poppy (Papaver s...

Determination of mitragynine in plasma with solid-phase extraction and rapid HPLC-UV analysis, and its application to a pharmacokinetic study in rat.

Anal. Bioanal. Chem 397(5) , 2023-30, (2010)

A new solid phase extraction method for rapid high performance liquid chromatography-UV determination of mitragynine in plasma has been developed. Optimal separation was achieved with an isocratic mob...

 Synonyms

9-Methoxycorynantheidine
mitragynine picrate
(16E,20b)-16,17-Didehydro-9,17-dimethoxycorynan-16-carboxylic Acid Methyl Ester
methyl (16E,20β)-9-methoxy-16-(methoxymethylidene)corynan-17-oate
Mitragynine
Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethyl-1,2,3,4,6,7,12,12b-octahydro-8-methoxy-α-(methoxymethylene)-, methyl ester, (αE,2S,3S,12bS)-
Methyl (16E,20β)-9,17-dimethoxycoryn-16-en-16-carboxylate
Corynan-16-carboxylic acid, 16,17-didehydro-9,17-dimethoxy-, methyl ester, (16E,20β)-
Mitragynine Crystal
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