(2R,3R,4R,5R)-2-(6-amino-2-methylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Modify Date: 2025-08-28 09:32:27

(2R,3R,4R,5R)-2-(6-amino-2-methylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol structure	Common Name	(2R,3R,4R,5R)-2-(6-amino-2-methylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
	CAS Number	4105-39-9	Molecular Weight	313.33
	Density	1.98g/cm3	Boiling Point	747.6ºC at 760 mmHg
	Molecular Formula	C₁₁H₁₅N₅O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	406ºC

Use of (2R,3R,4R,5R)-2-(6-amino-2-methylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

2-Methylthioadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-(6-amino-2-methylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Synonym	More Synonyms

Description	2-Methylthioadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. [2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

[2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.98g/cm3
Boiling Point	747.6ºC at 760 mmHg
Molecular Formula	C₁₁H₁₅N₅O₄S
Molecular Weight	313.33
Flash Point	406ºC
Exact Mass	313.08400
PSA	164.84000
Index of Refraction	1.878

2-MeS-adenosine

S-methyl-2-thio-isoguanosine

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

(2R,3R,4R,5R)-2-(6-amino-2-methylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Use of (2R,3R,4R,5R)-2-(6-amino-2-methylsulfanyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Names

Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.