Inophyllum B

Modify Date: 2024-01-10 18:42:33

Inophyllum B structure	Common Name	Inophyllum B
	CAS Number	41135-06-2	Molecular Weight	404.45500
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₄O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Inophyllum B

Inophyllum B ((+)-Inophyllum B) is a potent HIV Reverse Transcriptase inhibitor with an IC50 value of 38 nM. Inophyllum B inhibits HIV-1 (IC50=1.4 μM) in vitro cell culture. Inophyllum B can be isolated from the acetone extract of the giant African snail, Achatina fulica[1].

Name	(+)-inophyllum B
Synonym	More Synonyms

Description	Inophyllum B ((+)-Inophyllum B) is a potent HIV Reverse Transcriptase inhibitor with an IC50 value of 38 nM. Inophyllum B inhibits HIV-1 (IC50=1.4 μM) in vitro cell culture. Inophyllum B can be isolated from the acetone extract of the giant African snail, Achatina fulica[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Anti-infection >> Reverse Transcriptase
Target	HIV-1:1.4 μM (IC50) Reverse Transcriptase:38 nM (IC50)
References	[1]. Patil AD, et al. The inophyllums, novel inhibitors of HIV-1 reverse transcriptase isolated from the Malaysian tree, Calophyllum inophyllum Linn. J Med Chem. 1993 Dec 24;36(26):4131-8.

Molecular Formula	C₂₅H₂₄O₅
Molecular Weight	404.45500
Exact Mass	404.16200
PSA	68.90000
LogP	5.09460

(10R,11S,12S)-10,11-dihydro-12-hydroxy-4-phenyl-6,6,10,11-tetramethyl-2H,6H,12H-benzo[1,2-b:3,4-b':5,6-b'']tripyran-2-one

(10R,11S,12S)-12-Hydroxy-6,6,10,11-tetramethyl-4-phenyl-11,12-dihydro-6H,10H-dipyrano[2,3-f

2',3'-h]chromen-2-one

inophyllum B

inophyllum-B

Inophyllum B

Use of Inophyllum B

Names

Inophyllum B Biological Activity

Chemical & Physical Properties

Synonyms