Tolonidine
Modify Date: 2024-01-21 18:20:55
Tolonidine structure
|
Common Name | Tolonidine | ||
|---|---|---|---|---|
| CAS Number | 4201-22-3 | Molecular Weight | 209.67500 | |
| Density | 1.31g/cm3 | Boiling Point | 314ºC at 760 mmHg | |
| Molecular Formula | C10H12ClN3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 143.7ºC | |
Use of TolonidineTolonidine is a derivative of imidazoline. Tolonidine is orally active and has been shown to possess hypotensive and antihypertensive properties[1]. |
| Name | N-(2-chloro-4-methylphenyl)-4,5-dihydro-1H-imidazol-2-amine |
|---|---|
| Synonym | More Synonyms |
| Description | Tolonidine is a derivative of imidazoline. Tolonidine is orally active and has been shown to possess hypotensive and antihypertensive properties[1]. |
|---|---|
| Related Catalog | |
| In Vivo | In the anesthetized dog, tolonidine administered i.v. decreases the amplitude of ventricular contractions, reduces aortic blood flow and increases peripheral vascular resistances[1]. In the bivagotomized pithed rat, tolonidine induces a long-lasting increase in blood pressure with no secondary hypotension, thus suggesting peripheral sympathomimetic properties[1]. |
| References |
| Density | 1.31g/cm3 |
|---|---|
| Boiling Point | 314ºC at 760 mmHg |
| Molecular Formula | C10H12ClN3 |
| Molecular Weight | 209.67500 |
| Flash Point | 143.7ºC |
| Exact Mass | 209.07200 |
| PSA | 36.42000 |
| LogP | 1.85690 |
| Index of Refraction | 1.637 |
| HS Code | 2933290090 |
|---|
| HS Code | 2933290090 |
|---|---|
| Summary | 2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Tolonidina |
| Tolonidinum |
| ST-375 |
| Tolonidine |
| Euctan |