Mazaticol

Modify Date: 2024-01-20 13:30:36

Mazaticol Structure
Mazaticol structure
Common Name Mazaticol
CAS Number 42024-98-6 Molecular Weight 405.57
Density 1.28g/cm3 Boiling Point 528.7ºC at 760 mmHg
Molecular Formula C21H27NO3S2 Melting Point N/A
MSDS N/A Flash Point 273.5ºC

 Use of Mazaticol


Mazaticol is an anticholinergic agent. Mazaticol blocks the muscarinic acetylcholine receptors and cholinergic nerve activity. Mazaticol is a potent 3H-QNB and 3H-PZ binding inhibitor, can bind to the M2 receptors with high affinity. Mazaticol exhibits inhibitory effects on dopamine uptake in the striatal nerve terminal. Mazaticol can be used for parkinsonian syndrome research[1][2].

 Names

Name (6,6,9-trimethyl-9-azabicyclo[3.3.1]nonan-3-yl) 2-hydroxy-2,2-dithiophen-2-ylacetate
Synonym More Synonyms

 Mazaticol Biological Activity

Description Mazaticol is an anticholinergic agent. Mazaticol blocks the muscarinic acetylcholine receptors and cholinergic nerve activity. Mazaticol is a potent 3H-QNB and 3H-PZ binding inhibitor, can bind to the M2 receptors with high affinity. Mazaticol exhibits inhibitory effects on dopamine uptake in the striatal nerve terminal. Mazaticol can be used for parkinsonian syndrome research[1][2].
Related Catalog
References

[1]. Niimi Y, et al. Mazaticol for Treating Parkinson. 2020.

[2]. Katayama S, et al. Effects of anticholinergic antiparkinsonian drugs on binding of muscarinic receptor subtypes in rat brain. Res Commun Chem Pathol Pharmacol. 1990;69(3):261-270.

 Chemical & Physical Properties

Density 1.28g/cm3
Boiling Point 528.7ºC at 760 mmHg
Molecular Formula C21H27NO3S2
Molecular Weight 405.57
Flash Point 273.5ºC
Exact Mass 405.14300
PSA 106.25000
LogP 4.17800
Index of Refraction 1.624

 Synonyms

Mazaticol (INN)
6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl hydroxy(dithiophen-2-yl)acetate
Mazaticol
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