10H-Pyrido(2,3-b)pyrimido(4,5-e)(1,4)thiazine-2,4-diamine, 7-methoxy-

Modify Date: 2024-01-06 17:23:13

10H-Pyrido(2,3-b)pyrimido(4,5-e)(1,4)thiazine-2,4-diamine, 7-methoxy- Structure
10H-Pyrido(2,3-b)pyrimido(4,5-e)(1,4)thiazine-2,4-diamine, 7-methoxy- structure
Common Name 10H-Pyrido(2,3-b)pyrimido(4,5-e)(1,4)thiazine-2,4-diamine, 7-methoxy-
CAS Number 42362-20-9 Molecular Weight 262.29100
Density 1.544g/cm3 Boiling Point 609.2ºC at 760 mmHg
Molecular Formula C10H10N6OS Melting Point N/A
MSDS N/A Flash Point 322.2ºC

 Names

Name 7-methoxy-10H-pyrido[2,3-b]pyrimido[4,5-e][1,4]thiazine-2,4-diamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.544g/cm3
Boiling Point 609.2ºC at 760 mmHg
Molecular Formula C10H10N6OS
Molecular Weight 262.29100
Flash Point 322.2ºC
Exact Mass 262.06400
PSA 140.50000
LogP 1.27270
Index of Refraction 1.763

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV1173150
CHEMICAL NAME :
10H-Pyrido(2,3-b)pyrimido(4,5-e)(1,4)thiazine-2,4-dia mine, 7-methoxy-
CAS REGISTRY NUMBER :
42362-20-9
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H10-N6-O-S
MOLECULAR WEIGHT :
262.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 12,249,1977

 Synthetic Route

~%

10H-Pyrido(2,3-b)pyrimido(4,5-e)(1,4)thiazine-2,4-diamine, 7-methoxy- Structure

10H-Pyrido(2,3-...

CAS#:42362-20-9

Literature: Okafor Journal of Organic Chemistry, 1973 , vol. 38, # 26 p. 4386 - 4390

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

2,4-Diamino-7-methoxy-1,3,6-triazaphenothiazin