7-Hydroxymethyl-10,11-MDCPT

7-Hydroxymethyl-10,11-MDCPT structure	Common Name	7-Hydroxymethyl-10,11-MDCPT
	CAS Number	428816-69-7	Molecular Weight	422.39
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₁₈N₂O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 7-Hydroxymethyl-10,11-MDCPT

7-Hydroxymethyl-10,11-MDCPT is an analog of camptothecin. 7-Hydroxymethyl-10,11-MDCPT inhibits tumor cell line growth with IC50s of 230.9, 90.8, 404.5 nM against HeLa-S3, PC-3, and HT-29, respectively[1].

Name	7-Hydroxymethyl-10,11-MDCPT

Description	7-Hydroxymethyl-10,11-MDCPT is an analog of camptothecin. 7-Hydroxymethyl-10,11-MDCPT inhibits tumor cell line growth with IC50s of 230.9, 90.8, 404.5 nM against HeLa-S3, PC-3, and HT-29, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Wadkins RM, et al. Hydrophilic camptothecin analogs that form extremely stable cleavable complexes with DNA and topoisomerase I. Cancer Res. 2004 Sep 15;64(18):6679-83.

Molecular Formula	C₂₂H₁₈N₂O₇
Molecular Weight	422.39
InChIKey	UYOXKDDEJDVQSN-QFIPXVFZSA-N
SMILES	CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cc3c(cc1c2CO)OCO3

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