Z-Phe-Leu

Modify Date: 2024-01-02 20:44:46

Z-Phe-Leu Structure
Z-Phe-Leu structure
Common Name Z-Phe-Leu
CAS Number 4313-73-9 Molecular Weight 412.47900
Density 1.193g/cm3 Boiling Point 674.4ºC at 760mmHg
Molecular Formula C23H28N2O5 Melting Point N/A
MSDS Chinese USA Flash Point 361.7ºC

 Use of Z-Phe-Leu


Z-Phe-Leu-OH (NSC 334018) is a substrate for carboxypeptidase Y (CPY). Z-Phe-Leu-OH is incubated with recombinant CPY to determine peptidase activity[1].

 Names

Name 4-methyl-2-[[3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]pentanoic acid
Synonym More Synonyms

 Z-Phe-Leu Biological Activity

Description Z-Phe-Leu-OH (NSC 334018) is a substrate for carboxypeptidase Y (CPY). Z-Phe-Leu-OH is incubated with recombinant CPY to determine peptidase activity[1].
Related Catalog
References

[1]. Makino M, et, al. Carboxypeptidase Y activity and maintenance is modulated by a large helical structure. FEBS Open Bio. 2019 Jul;9(7):1337-1343.

 Chemical & Physical Properties

Density 1.193g/cm3
Boiling Point 674.4ºC at 760mmHg
Molecular Formula C23H28N2O5
Molecular Weight 412.47900
Flash Point 361.7ºC
Exact Mass 412.20000
PSA 104.73000
LogP 3.92140
Index of Refraction 1.564
Storage condition -20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Precursor & DownStream

Precursor  0

DownStream  1

 Articles5

More Articles
Amphipathic property of free thiol group contributes to an increase in the catalytic efficiency of carboxypeptidase Y.

Eur. J. Biochem. 269 , 3220-3225, (2002)

Cys341 of carboxypeptidase Y, which constitutes one side of the solvent-accessible surface of the S1 binding pocket, was replaced with Gly, Ser, Asp, Val, Phe or His by site-directed mutagenesis. Kine...

Debittering effect of Actinomucor elegans peptidases on soybean protein hydrolysates.

J. Ind. Microbiol. Biotechnol. 35 , 41-47, (2008)

Effects of the enzymes in Actinomucor elegans extract and the enzyme Alcalase 2.4L on debittering the soybean protein hydrolysates were investigated. When the protein was treated only with the latter,...

Characterization of a bifunctional aminoacylase/carboxypeptidase from radioresistant bacterium Deinococcus radiodurans R1.

J. Biotechnol. 128 , 322-334, (2007)

The gene encoding a Deinococcus radiodurans R1 bifunctional aminoacylase/carboxypeptidase (DR_ACY/CP) was amplified by polymerase chain reaction and cloned into pQE-30 to generate pQE-DRAC. The cloned...

 Synonyms

Cbz-L-Phe-L-Leu-OH
Z-Phe-Leu
N-CBZ-Phe-Leu
N-Benzyloxycarbonyl-L-phenylalanyl-L-leucin
Z-Phe-Leu-OH
Cbz-Phe-Leu-OH
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