4,4-dimethyl[1,1-biphenyl]-2,2,5,5-tetrol

Modify Date: 2024-01-14 12:42:33

4,4-dimethyl[1,1-biphenyl]-2,2,5,5-tetrol Structure
4,4-dimethyl[1,1-biphenyl]-2,2,5,5-tetrol structure
 Common Name 4,4-dimethyl[1,1-biphenyl]-2,2,5,5-tetrol
CAS Number 4371-34-0 Molecular Weight 246.25900
Density 1.36g/cm3 Boiling Point 501.6ºC at 760 mmHg
Molecular Formula C14H14O4 Melting Point N/A
MSDS N/A Flash Point 248.2ºC

 Use of 4,4-dimethyl[1,1-biphenyl]-2,2,5,5-tetrol


NSC2805 is a WWP2 ubiquitin ligase inhibitor that can significant inhibit WWP2 activity with an IC50 of 0.38 μM. NSC2805 can be used for the research of cancer[1].

 Names

Name 2-(2,5-dihydroxy-4-methylphenyl)-5-methylbenzene-1,4-diol
Synonym More Synonyms

  Biological Activity

Description NSC2805 is a WWP2 ubiquitin ligase inhibitor that can significant inhibit WWP2 activity with an IC50 of 0.38 μM. NSC2805 can be used for the research of cancer[1].
Related Catalog
In Vitro NSC2805 has WWP2 inhibitory activity with an IC50 of 0.38 μM[1]. NSC2805 shows a significant reduction in activity for all three proteins (WWP2, WWP1 and Nedd4)[1]. NSC2805 can robustly inhibit WWP2-dependent PTEN ubiquitination[1].
References

[1]. Jessica E Watt, et al. Discovery of Small Molecule WWP2 Ubiquitin Ligase Inhibitors. Chemistry. 2018 Dec 3;24(67):17677-17680.

 Chemical & Physical Properties

Density 1.36g/cm3
Boiling Point 501.6ºC at 760 mmHg
Molecular Formula C14H14O4
Molecular Weight 246.25900
Flash Point 248.2ºC
Exact Mass 246.08900
PSA 80.92000
LogP 2.79280
Index of Refraction 1.675

 Safety Information

HS Code 2906299090

 Customs

HS Code 2906299090
Summary 2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Synonyms

4.4'-Dimethyl-biphenyltetrol-(2.5.2'.5')
2.5.2'.5'-Tetraoxy-4.4'-dimethyl-diphenyl
2.5.2'.5'-Tetrahydroxy-4.4'-dimethyl-biphenyl
2.5.2'.5'-Tetraoxy-ditolyl-(4.4')
4,4'-dimethyl[1,1'-biphenyl]-2,2',5,5'-tetrol
4,4'-Dimethyl-biphenyl-2,5,2',5'-tetraol
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Chemsrc provides CAS#:4371-34-0 MSDS, density, melting point, boiling point, structure, etc. Its name is 4,4-dimethyl[1,1-biphenyl]-2,2,5,5-tetrol>> amp version: 4,4-dimethyl[1,1-biphenyl]-2,2,5,5-tetrol

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