ReAsH-EDT2

Modify Date: 2026-08-06 11:58:09

ReAsH-EDT2 Structure
ReAsH-EDT2 structure
Common Name ReAsH-EDT2
CAS Number 438226-89-2 Molecular Weight 545.38300
Density N/A Boiling Point N/A
Molecular Formula C16H13As2NO3S4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ReAsH-EDT2


ReAsH-EDT2 is a red fluorescent dye that marks proteins. ReAsH-EDT2 is a membrane-permeable biarsenical compound that binds covalently to tetracysteine sequences which allows the protein to be imaged. ReAsH-EDT2 can be used for protein localization and trafficking. (λex=530 nm, λem=592 nm)[1][2].

 Names

Name 4,6-bis(1,3,2-dithiarsolan-2-yl)-7-hydroxyphenoxazin-3-one
Synonym More Synonyms

 ReAsH-EDT2 Biological Activity

Description ReAsH-EDT2 is a red fluorescent dye that marks proteins. ReAsH-EDT2 is a membrane-permeable biarsenical compound that binds covalently to tetracysteine sequences which allows the protein to be imaged. ReAsH-EDT2 can be used for protein localization and trafficking. (λex=530 nm, λem=592 nm)[1][2].
Related Catalog
In Vitro ReAsH-EDT2 tags with GyrB.FGFR1KD.TC can appear with red fluorescence.
References

[1]. Adams SR, et, al. Preparation of the membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH-EDT2 for fluorescent labeling of tetracysteine-tagged proteins. Nat Protoc. 2008;3(9):1527-34.

[2]. Perdios L, et, al. Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1. Adv Biol Regul. 2016 Jan;60:6-13.

 Chemical & Physical Properties

Molecular Formula C16H13As2NO3S4
Molecular Weight 545.38300
Exact Mass 544.82100
PSA 164.53000
LogP 2.34880
InChIKey UNIBJWQHKWCMGJ-UHFFFAOYSA-N
SMILES O=c1ccc2nc3ccc(O)c([As]4SCCS4)c3oc-2c1[As]1SCCS1

 ReAsH-EDT2Bioassay

View more

Name: Inhibition of allosterically sensitized mutant form of His6-tagged human HePTP cataly...
Source: ChEMBL
Target: Tyrosine-protein phosphatase non-receptor type 7
External Id: CHEMBL4121953
Name: Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C...
Source: ChEMBL
Target: Tyrosine-protein phosphatase non-receptor type 1
External Id: CHEMBL4121935
Name: Inhibition of His6-tagged human wild-type HePTP catalytic domain at 1 uM using pNPP a...
Source: ChEMBL
Target: Tyrosine-protein phosphatase non-receptor type 7
External Id: CHEMBL4121952
Name: Inhibition of allosterically sensitized mutant form of His6-tagged human HePTP cataly...
Source: ChEMBL
Target: Tyrosine-protein phosphatase non-receptor type 7
External Id: CHEMBL4121949
Name: Inhibition of His6-tagged human wild-type PTP catalytic domain at 500 nM using pNPP a...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4121950
Name: Inhibition of allosterically sensitized mutant form of His6-tagged human FAP1 catalyt...
Source: ChEMBL
Target: Tyrosine-protein phosphatase non-receptor type 13
External Id: CHEMBL4121963
Name: Inhibition of allosterically sensitized mutant form of His6-tagged human SHP1 catalyt...
Source: ChEMBL
Target: Tyrosine-protein phosphatase non-receptor type 6
External Id: CHEMBL4121961
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 Synonyms

Lumio Red
ReAsH-EDT2
3H-Phenoxazin-3-one,4,6-di-1,3,2-dithiarsolan-2-yl-7-hydroxy
4,6-Di-1,3,2-dithiarsolan-2-yl-7-hydroxy-3H-phenoxazin-3-one
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