ReAsH-EDT2

Modify Date: 2024-01-02 14:31:02

ReAsH-EDT2 Structure
ReAsH-EDT2 structure
Common Name ReAsH-EDT2
CAS Number 438226-89-2 Molecular Weight 545.38300
Density N/A Boiling Point N/A
Molecular Formula C16H13As2NO3S4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ReAsH-EDT2


ReAsH-EDT2 is a red fluorescent dye that marks proteins. ReAsH-EDT2 is a membrane-permeable biarsenical compound that binds covalently to tetracysteine sequences which allows the protein to be imaged. ReAsH-EDT2 can be used for protein localization and trafficking. (λex=530 nm, λem=592 nm)[1][2].

 Names

Name 4,6-bis(1,3,2-dithiarsolan-2-yl)-7-hydroxyphenoxazin-3-one
Synonym More Synonyms

 ReAsH-EDT2 Biological Activity

Description ReAsH-EDT2 is a red fluorescent dye that marks proteins. ReAsH-EDT2 is a membrane-permeable biarsenical compound that binds covalently to tetracysteine sequences which allows the protein to be imaged. ReAsH-EDT2 can be used for protein localization and trafficking. (λex=530 nm, λem=592 nm)[1][2].
Related Catalog
In Vitro ReAsH-EDT2 tags with GyrB.FGFR1KD.TC can appear with red fluorescence.
References

[1]. Adams SR, et, al. Preparation of the membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH-EDT2 for fluorescent labeling of tetracysteine-tagged proteins. Nat Protoc. 2008;3(9):1527-34.

[2]. Perdios L, et, al. Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1. Adv Biol Regul. 2016 Jan;60:6-13.

 Chemical & Physical Properties

Molecular Formula C16H13As2NO3S4
Molecular Weight 545.38300
Exact Mass 544.82100
PSA 164.53000
LogP 2.34880

 Synonyms

Lumio Red
ReAsH-EDT2
3H-Phenoxazin-3-one,4,6-di-1,3,2-dithiarsolan-2-yl-7-hydroxy
4,6-Di-1,3,2-dithiarsolan-2-yl-7-hydroxy-3H-phenoxazin-3-one