KOdiA-PC

Modify Date: 2024-02-28 12:22:29

KOdiA-PC Structure
KOdiA-PC structure
Common Name KOdiA-PC
CAS Number 439904-33-3 Molecular Weight 663.777
Density N/A Boiling Point N/A
Molecular Formula C32H58NO11P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of KOdiA-PC


Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.

 Names

Name KOdiA-PC
Synonym More Synonyms

 KOdiA-PC Biological Activity

Description Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.
Related Catalog

 Chemical & Physical Properties

Molecular Formula C32H58NO11P
Molecular Weight 663.777
Exact Mass 663.374756
PSA 175.37000
LogP 3.50

 Synonyms

(2R)-2-{[(6E)-7-Carboxy-5-oxo-6-heptenoyl]oxy}-3-(palmitoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
Ethanaminium, 2-[[[(2R)-2-[[(6E)-7-carboxy-1,5-dioxo-6-hepten-1-yl]oxy]-3-[(1-oxohexadecyl)oxy]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt