2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid
2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid structure
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Common Name | 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid | ||
|---|---|---|---|---|
| CAS Number | 441-28-1 | Molecular Weight | 267.25500 | |
| Density | 1.344g/cm3 | Boiling Point | 453.7ºC at 760mmHg | |
| Molecular Formula | C16H10FNO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 228.2ºC | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.344g/cm3 |
|---|---|
| Boiling Point | 453.7ºC at 760mmHg |
| Molecular Formula | C16H10FNO2 |
| Molecular Weight | 267.25500 |
| Flash Point | 228.2ºC |
| Exact Mass | 267.07000 |
| PSA | 50.19000 |
| LogP | 3.73910 |
| Vapour Pressure | 5.06E-09mmHg at 25°C |
| Index of Refraction | 1.663 |
| InChIKey | OSSAIQFBELCOGQ-UHFFFAOYSA-N |
| SMILES | O=C(O)c1cc(-c2ccc(F)cc2)nc2ccccc12 |
This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| HS Code | 2933499090 |
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This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~95%
2-(4-fluoro-phe... CAS#:441-28-1 |
| Literature: Nicolaie, E; Guengoer, T; Goyard, J; Cure, G; Fouquet, A; et al. European Journal of Medicinal Chemistry, 1992 , vol. 27, # 9 p. 977 - 984 |
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~68%
2-(4-fluoro-phe... CAS#:441-28-1 |
| Literature: Aboul-Enein, Hassan Y.; Ibrahim, Said E. Journal of Fluorine Chemistry, 1992 , vol. 59, # 2 p. 233 - 237 |
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~%
2-(4-fluoro-phe... CAS#:441-28-1 |
| Literature: Buu-Hoi; Hoan; Jacquignon Recueil des Travaux Chimiques des Pays-Bas, 1949 , vol. 68, p. 781,785 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 5 | |
|---|---|
| DownStream 0 | |
This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Screen for inhibitors of RMI FANCM (MM2) intereaction
Source: 11908
Target: N/A
External Id: RMI-FANCM-MM2
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Name: Alphascreen assay for small molecules abrogating mHTT-CaM Interaction
Source: 24983
Target: Huntingtin
External Id: KUHTS-Muma KU-CaM-Htt INH-01
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Name: Cell-based high throughput primary assay to identify activators of GPR151
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL
External Id: GPR151_PHUNTER_AG_LUMI_1536_1X%ACT
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|
Name: AlphaScreen-based biochemical high throughput primary assay to identify activators of...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: FBW7_ACT_ALPHA_1536_1X%ACT PRUN
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Name: AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of...
Source: The Scripps Research Institute Molecular Screening Center
External Id: MITF_INH_Alpha_1536_1X%INH PRUN
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| iflab-bb f0239-0170 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the LogP of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid? |
| A: LogP of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid is 3.73910. |
| Q: What is the polar surface area (PSA) of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid? |
| A: Polar surface area (PSA) of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid is 50.19000. |
| Q: What is the boiling point of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid? |
| A: Boiling point of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid is 453.7ºC at 760mmHg. |
| Q: What is the InChIKey of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid? |
| A: InChIKey of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid is OSSAIQFBELCOGQ-UHFFFAOYSA-N. |
| Q: What is the English name of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid? |
| A: The English name of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid is 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid. |
| Q: What is the SMILES notation of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid? |
| A: SMILES notation of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid is O=C(O)c1cc(-c2ccc(F)cc2)nc2ccccc12. |
| Q: What are the upstream materials of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid? |
| A: Related upstream materials(CAS) of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid: 91-56-5;403-42-9;459-57-4;127-17-3;462-06-6. |
| Q: What is the molecular weight of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid? |
| A: Molecular weight of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid is 267.25500. |
| Q: What is the molecular formula of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid? |
| A: Molecular formula of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid is C16H10FNO2. |
| Q: What is the CAS number of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid? |
| A: CAS number of 2-(4-fluoro-phenyl)-quinoline-4-carboxylic acid is 441-28-1. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |