Cc-3060

Modify Date: 2025-08-25 15:15:31

Cc-3060 Structure
Cc-3060 structure
Common Name Cc-3060
CAS Number 444288-86-2 Molecular Weight 403.39
Density N/A Boiling Point N/A
Molecular Formula C22H17N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cc-3060


CC-3060 is a Cereblon modulator that promotes ZBTB16 degradation. CC-3060 degrades ZBTB16 with a DC50 of 0.47 nM in HT-1080 cells. CC-3060 targets ZBTB16 for degradation by primarily engaging distinct structural degrons on different zinc finger domains[1].

 Names

Name CC-3060

 Cc-3060 Biological Activity

Description CC-3060 is a Cereblon modulator that promotes ZBTB16 degradation. CC-3060 degrades ZBTB16 with a DC50 of 0.47 nM in HT-1080 cells. CC-3060 targets ZBTB16 for degradation by primarily engaging distinct structural degrons on different zinc finger domains[1].
Related Catalog
Target

DC50: 0.47 nM (ZBTB16 in HT-1080 cells)[1]

References

[1]. Matyskiela ME, et al. Cereblon Modulators Target ZBTB16 and Its Oncogenic Fusion Partners for Degradation via Distinct Structural Degrons. ACS Chem Biol. 2020 Dec 18;15(12):3149-3158.

 Chemical & Physical Properties

Molecular Formula C22H17N3O5
Molecular Weight 403.39
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