BBT

Modify Date: 2024-01-11 23:23:05

BBT Structure
BBT structure
Common Name BBT
CAS Number 445000-45-3 Molecular Weight 386.26
Density N/A Boiling Point N/A
Molecular Formula C18H12BrNO2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BBT


BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS). BBT exhibits anti-hyperglycemia activity, and protects β-cells from cytokine- or streptozotocin (STZ)-induced cell death in type 2 diabetes models. BBT acts function via cAMP/PKA and long-lasting (L-type) voltage-dependent Ca2+ channel/CaMK2 pathway[1].

 Names

Name BBT

 BBT Biological Activity

Description BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS). BBT exhibits anti-hyperglycemia activity, and protects β-cells from cytokine- or streptozotocin (STZ)-induced cell death in type 2 diabetes models. BBT acts function via cAMP/PKA and long-lasting (L-type) voltage-dependent Ca2+ channel/CaMK2 pathway[1].
Related Catalog
Target

L-type voltage-dependent Ca2+ channel/CaMK2[1]

References

[1]. Yao XG, et al. BBT improves glucose homeostasis by ameliorating 尾-cell dysfunction in type 2 diabetic mice. J Endocrinol. 2015 Mar;224(3):327-41.  

 Chemical & Physical Properties

Molecular Formula C18H12BrNO2S
Molecular Weight 386.26