2-[(Thiophen-2-yl)methyl]malonic acid

Modify Date: 2025-10-01 17:14:07

2-[(Thiophen-2-yl)methyl]malonic acid Structure
2-[(Thiophen-2-yl)methyl]malonic acid structure
Common Name 2-[(Thiophen-2-yl)methyl]malonic acid
CAS Number 4475-24-5 Molecular Weight 200.21200
Density 1.489g/cm3 Boiling Point 390.3ºC at 760 mmHg
Molecular Formula C8H8O4S Melting Point 140 ºC (benzene )
MSDS N/A Flash Point 189.8ºC

 Names

Name 2-(thiophen-2-ylmethyl)propanedioic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.489g/cm3
Boiling Point 390.3ºC at 760 mmHg
Melting Point 140 ºC (benzene )
Molecular Formula C8H8O4S
Molecular Weight 200.21200
Flash Point 189.8ºC
Exact Mass 200.01400
PSA 102.84000
LogP 1.07600
Index of Refraction 1.609
InChIKey PGGOEUVKDHKGKQ-UHFFFAOYSA-N
SMILES O=C(O)C(Cc1cccs1)C(=O)O
Water Solubility Sparingly soluble (11 g/L) (25 ºC)

 Safety Information

RIDADR NONH for all modes of transport

 Synthetic Route

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2-[(Thiophen-2-yl)methyl]malonic acid Structure

2-[(Thiophen-2-...

CAS#:4475-24-5

Literature: Blicke; Leonard Journal of the American Chemical Society, 1946 , vol. 68, p. 1934 Full Text View citing articles Show Details Cagniant; Cagniant Bulletin de la Societe Chimique de France, 1954 , p. 1349,1353

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2-[(Thiophen-2-yl)methyl]malonic acid Structure

2-[(Thiophen-2-...

CAS#:4475-24-5

Literature: Blicke; Leonard Journal of the American Chemical Society, 1946 , vol. 68, p. 1934 Full Text View citing articles Show Details Cagniant; Cagniant Bulletin de la Societe Chimique de France, 1954 , p. 1349,1353

~%

2-[(Thiophen-2-yl)methyl]malonic acid Structure

2-[(Thiophen-2-...

CAS#:4475-24-5

Literature: Westfahl; Gresham Journal of the American Chemical Society, 1954 , vol. 76, p. 1076,1077

 2-[(Thiophen-2-yl)methyl]malonic acidBioassay

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Name: Assays to identify small molecules inhibitory for eIF4E expression
Source: 13133
Target: N/A
External Id: 20160513eIF4E
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 Synonyms

thien-2-ylmethyl-malonic acid
2-thiopheneylmethylmalonic acid
2-[(Thiophen-2-yl)methyl]malonic acid
Eprosartan Impurity 3
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