N-Methyl-β-chloroethylamine hydrochloride

Modify Date: 2024-01-02 17:34:18

N-Methyl-β-chloroethylamine hydrochloride Structure
N-Methyl-β-chloroethylamine hydrochloride structure
Common Name N-Methyl-β-chloroethylamine hydrochloride
CAS Number 4535-90-4 Molecular Weight 130.016
Density N/A Boiling Point 110.3ºC at 760mmHg
Molecular Formula C3H9Cl2N Melting Point N/A
MSDS N/A Flash Point 20.5ºC

 Names

Name 2-Methylaminoethyl Chloride Hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 110.3ºC at 760mmHg
Molecular Formula C3H9Cl2N
Molecular Weight 130.016
Flash Point 20.5ºC
Exact Mass 129.011200
PSA 12.03000
LogP 1.63750

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 2-Methylaminoethyl chloride HCl
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:2-Methylaminoethyl chloride HCl
CAS number:4535-90-4

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C3H8ClN.ClH
Molecular weight:130.0

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KR1950000
CHEMICAL NAME :
Ethylamine, 2-chloro-N-methyl-, hydrochloride
CAS REGISTRY NUMBER :
4535-90-4
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C3-H8-Cl-N.Cl-H
MOLECULAR WEIGHT :
130.03
WISWESSER LINE NOTATION :
G2M1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2301 mg/kg
TOXIC EFFECTS :
Behavioral - ataxia
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 94,249,1948
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 91,224,1947

 Safety Information

HS Code 2921199090

 Synthetic Route

~98%

N-Methyl-β-chloroethylamine hydrochloride Structure

N-Methyl-β-chlo...

CAS#:4535-90-4

Literature: University of Rochester Patent: US5233031 A1, 1993 ;

~80%

N-Methyl-β-chloroethylamine hydrochloride Structure

N-Methyl-β-chlo...

CAS#:4535-90-4

Literature: CENTAURUS BIOPHARMA CO., LTD.; XIAO, Dengming; ZHU, Li; HU, Yuandong; YU, Rong; HU, Wei; ZHAO, Na; PENG, Yong; LUO, Hong; HAN, Yongxin Patent: WO2013/97773 A1, 2013 ; Location in patent: Paragraph 0236; 0312 ;

~%

N-Methyl-β-chloroethylamine hydrochloride Structure

N-Methyl-β-chlo...

CAS#:4535-90-4

Literature: Marckwald; Frobenius Chemische Berichte, 1901 , vol. 34, p. 3549

 Customs

HS Code 2921199090
Summary 2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

2-Chloro-N-methylethanamine Hydrochloride
Ethanamine, 2-chloro-N-methyl-, hydrochloride (1:1)
N-Methyl-β-chloroethylamine hydrochloride
2-Chloro-N-methylethanamine hydrochloride (1:1)
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