6-amino-8-(3-furyl)-2-isopropyl-2,3,8,8a-tetrahydro-5,7,7(1H)-isoquinolinetricarbonitrile

Modify Date: 2026-04-01 21:52:07

6-amino-8-(3-furyl)-2-isopropyl-2,3,8,8a-tetrahydro-5,7,7(1H)-isoquinolinetricarbonitrile Structure
6-amino-8-(3-furyl)-2-isopropyl-2,3,8,8a-tetrahydro-5,7,7(1H)-isoquinolinetricarbonitrile structure
Common Name 6-amino-8-(3-furyl)-2-isopropyl-2,3,8,8a-tetrahydro-5,7,7(1H)-isoquinolinetricarbonitrile
CAS Number 459155-01-2 Molecular Weight 333.4
Density N/A Boiling Point N/A
Molecular Formula C19H19N5O Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 6-amino-8-(3-furyl)-2-isopropyl-2,3,8,8a-tetrahydro-5,7,7(1H)-isoquinolinetricarbonitrile

 Chemical & Physical Properties

Molecular Formula C19H19N5O
Molecular Weight 333.4
InChIKey LPYIGKHKQBNYRP-DLBZAZTESA-N
SMILES CC(C)N1CC=C2[C@H](C1)[C@H](C(C(=C2C#N)N)(C#N)C#N)C3=COC=C3

 Bioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Fluorescence-based counterscreen for orexin 1 receptor (OX1R) antagonists: cell-based...
Source: The Scripps Research Institute Molecular Screening Center
Target: N/A
External Id: CHOK1_ANT_FLUO8_1536_1X%INH CSRUN
Name: Absorbance-based primary biochemical high throughput screening assay to identify acti...
Source: The Scripps Research Institute Molecular Screening Center
Target: caspase-3 preproprotein [Homo sapiens]
External Id: PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN
Name: HTS to identify inhibitors of TNF-alpha Induced Cell Death in Jurkat FADD-/- Cells.
Source: University of Pittsburgh Molecular Library Screening Center
Target: N/A
External Id: MH081226: Primary HTS for Inhibitors of a Novel Necrotic Cell Death Pathway # Jurkat FADD-/- Model.
Name: Primary cell-based high-throughput screening for identification of compounds that all...
Source: Johns Hopkins Ion Channel Center
Target: MAS-related GPR member X1 [Homo sapiens]
External Id: JHICC_MrgX1_AlloAgonist_Primary
Name: Primary cell-based high-throughput screening for identification of compounds that ant...
Source: Johns Hopkins Ion Channel Center
Target: MAS-related GPR member X1 [Homo sapiens]
External Id: JHICC_MrgX1_Antagonist_Primary
Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
Name: Counterscreen for procaspase-3 activators: absorbance-based primary biochemical high ...
Source: The Scripps Research Institute Molecular Screening Center
Target: caspase 7, apoptosis-related cysteine peptidase [Homo sapiens]
External Id: PROCASPASE7_ACT_EPIABS_1536_1X%ACT CSRUN
Name: Fluorescence polarization-based primary biochemical high throughput screening assay t...
Source: The Scripps Research Institute Molecular Screening Center
Target: platelet-activating factor acetylhydrolase precursor [Homo sapiens]
External Id: PPAFAH_INH_FP_1536_1X%INH PRUN
Name: 384-well Z-Lyte format Hck-Nef inhibitor HTS run at the PMLSC
Source: University of Pittsburgh Molecular Library Screening Center
Target: N/A
External Id: MH083223 Targeting HIV-1 Nef with Small Molecules
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