GT 949
Modify Date: 2024-01-12 16:45:59
GT 949 structure
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Common Name | GT 949 | ||
|---|---|---|---|---|
| CAS Number | 460330-27-2 | Molecular Weight | 527.66 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H37N7O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GT 949GT 949 is a selective excitatory amino acid transporter-2 (EAAT2) positive allosteric modulator with an EC50 of 0.26 nM[1]. |
| Name | GT 949 |
|---|
| Description | GT 949 is a selective excitatory amino acid transporter-2 (EAAT2) positive allosteric modulator with an EC50 of 0.26 nM[1]. |
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| Related Catalog | |
| Target |
EC50: 0.26±0.03 nM (EAAT2)[1] |
| In Vitro | GT 949 (GT949) enhances glutamate transport with an EC50 of 0.26 ± 0.03 nM. GT 949 also demonstrates selectivity to EAAT2 and has no effect on glutamate activity mediated by EAAT1 or EAAT3[1]. GT 949 is also tested for its effect on glutamate uptake kinetics in EAAT2-transfected cells. GT 949 enhances glutamate transport in a noncompetitive fashion, with increase in Vmax of about 47%[1]. |
| References |
| Molecular Formula | C30H37N7O2 |
|---|---|
| Molecular Weight | 527.66 |
| Storage condition | 2-8℃ |