ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate

Modify Date: 2026-07-12 09:31:31

ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate Structure
ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate structure
Common Name ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate
CAS Number 4610-75-7 Molecular Weight 282.29100
Density 1.257g/cm3 Boiling Point 471.3ºC at 760 mmHg
Molecular Formula C17H14O4 Melting Point N/A
MSDS N/A Flash Point 238.8ºC

Summary: ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate (Chinese name: 5-羟基-2-苯基苯并呋喃-3-羧酸乙酯,CAS number: 4610-75-7), molecular formula: C17H14O4,molecular weight: 282.29100,for research-use only, not for medical or clinical usage.


 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.257g/cm3
Boiling Point 471.3ºC at 760 mmHg
Molecular Formula C17H14O4
Molecular Weight 282.29100
Flash Point 238.8ºC
Exact Mass 282.08900
PSA 59.67000
LogP 3.98210
Index of Refraction 1.624
InChIKey WZZJQHPNLFLEMB-UHFFFAOYSA-N
SMILES CCOC(=O)c1c(-c2ccccc2)oc2ccc(O)cc12

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: Ethyl 5-hydroxy-2-phenylbenzofuran-3-carboxylate
Synonyms:5-Hydroxy-2-phenyl-benzofuran-3-carboxylic acid ethyl ester

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:Ethyl 5-hydroxy-2-phenylbenzofuran-3-carboxylate
CAS number:4610-75-7

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C17H14O4
Molecular weight:282.3

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~97%

ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate Structure

ethyl 5-hydroxy...

CAS#:4610-75-7

Learn More
Literature: Thirupathaiah; Venkateshwar Rao; Ramanna Oriental Journal of Chemistry, 2010 , vol. 26, # 4 p. 1521 - 1524

~61%

ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate Structure

ethyl 5-hydroxy...

CAS#:4610-75-7

Learn More
Literature: Liu, Jingxin; Liu, Yingjie; Du, Wenting; Dong, Ying; Liu, Jun; Wang, Mang Journal of Organic Chemistry, 2013 , vol. 78, # 14 p. 7293 - 7297

~%

ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate Structure

ethyl 5-hydroxy...

CAS#:4610-75-7

Learn More
Literature: Yadav, Pratima; Singh, Praveen; Tewari, Ashish Kumar Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 10 p. 2251 - 2255

~%

ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate Structure

ethyl 5-hydroxy...

CAS#:4610-75-7

Learn More
Literature: Grinew et al. Zhurnal Obshchei Khimii, 1957 , vol. 27, p. 821; engl. Ausg. S. 897

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  4

DownStream  1

 Bioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Inhibition of PKS13 in Mycobacterium tuberculosis H37Rv assessed as reduction in bact...
Source: ChEMBL
Target: N/A
External Id: CHEMBL4059067
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

2-Phenyl-3-ethoxycarbonyl-5-hydroxybenzofuran
ethyl 5-hydroxy-2-phenylbenzofuran-3-carboxylate
2-Phenyl-3-carbaethoxy-5-hydroxybenzofuran
3-ethoxycarbonyl-5-hydroxy-2-phenyl-1-benzofuran
5-Hydroxy-2-phenyl-benzofuran-3-carbonsaeure-aethylester
5-Hydroxy-2-phenyl-benzofuran-3-carboxylic acid ethyl ester

  | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the molecular weight of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate?
A: Molecular weight of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate is 282.29100.
Q: What are the upstream materials of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate?
A: Related upstream materials(CAS) of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate: 94-02-0;106-51-4;98-80-6;123-31-9.
Q: What is the SMILES notation of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate?
A: SMILES notation of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate is CCOC(=O)c1c(-c2ccccc2)oc2ccc(O)cc12.
Q: What is the molecular formula of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate?
A: Molecular formula of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate is C17H14O4.
Q: What English synonyms does ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate have?
A: English synonyms of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate: 2-Phenyl-3-ethoxycarbonyl-5-hydroxybenzofuran, ethyl 5-hydroxy-2-phenylbenzofuran-3-carboxylate, 2-Phenyl-3-carbaethoxy-5-hydroxybenzofuran, 3-ethoxycarbonyl-5-hydroxy-2-phenyl-1-benzofuran, 5-Hydroxy-2-phenyl-benzofuran-3-carbonsaeure-aethylester, 5-Hydroxy-2-phenyl-benzofuran-3-carboxylic acid ethyl ester.
Q: What is the English name of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate?
A: The English name of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate is ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate.
Q: What is the CAS number of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate?
A: CAS number of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate is 4610-75-7.
Q: What is the LogP of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate?
A: LogP of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate is 3.98210.
Q: What are the downstream products of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate?
A: Related downstream products(CAS) of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate: 7182-29-8.
Q: What is the polar surface area (PSA) of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate?
A: Polar surface area (PSA) of ethyl 5-hydroxy-2-phenyl-1-benzofuran-3-carboxylate is 59.67000.

 factory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Hubei Changfu Chemical Co., Ltd.
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