CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
BV8151500
-
CHEMICAL NAME :
-
Androst-4-ene-3,11-dione, 9-fluoro-17-beta-hydroxy-17-methyl-
-
CAS REGISTRY NUMBER :
-
465-69-0
-
BEILSTEIN REFERENCE NO. :
-
3163272
-
LAST UPDATED :
-
199612
-
DATA ITEMS CITED :
-
3
-
MOLECULAR FORMULA :
-
C20-H27-F-O3
-
MOLECULAR WEIGHT :
-
334.47
-
WISWESSER LINE NOTATION :
-
L E5 B666 CV OV MUTJ A1 BF E1 FQ F1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
DOSE :
-
800 mg/kg
-
SEX/DURATION :
-
female 3-10 day(s) after conception
-
TOXIC EFFECTS :
-
Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - abortion
-
REFERENCE :
-
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 39,319,1974
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
DOSE :
-
500 mg/kg
-
SEX/DURATION :
-
female 3-7 day(s) after conception
-
TOXIC EFFECTS :
-
Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
-
REFERENCE :
-
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 39,319,1974
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
DOSE :
-
12 mg/kg
-
SEX/DURATION :
-
female 3 day(s) pre-mating
-
TOXIC EFFECTS :
-
Reproductive - Maternal Effects - uterus, cervix, vagina
-
REFERENCE :
-
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 39,319,1974
|
