Steviol

Modify Date: 2025-08-21 20:47:43

Steviol Structure
Steviol structure
Common Name Steviol
CAS Number 471-80-7 Molecular Weight 318.450
Density 1.2±0.1 g/cm3 Boiling Point 464.5±45.0 °C at 760 mmHg
Molecular Formula C20H30O3 Melting Point 215°
MSDS Chinese USA Flash Point 248.8±25.2 °C

 Use of Steviol


Steviol is a major metabolite of the sweetening compound stevioside. Steviol slows renal cyst growth by reducing AQP2 expression and promoting AQP2 degradation[1].

 Names

Name (4R)-13-Hydroxykaur-16-en-18-oic acid
Synonym More Synonyms

 Steviol Biological Activity

Description Steviol is a major metabolite of the sweetening compound stevioside. Steviol slows renal cyst growth by reducing AQP2 expression and promoting AQP2 degradation[1].
Related Catalog
References

[1]. Noitem R, et al. Steviol slows renal cyst growth by reducing AQP2 expression and promoting AQP2 degradation. Biomed Pharmacother. 2018 May;101:754-762.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 464.5±45.0 °C at 760 mmHg
Melting Point 215°
Molecular Formula C20H30O3
Molecular Weight 318.450
Flash Point 248.8±25.2 °C
Exact Mass 318.219482
PSA 57.53000
LogP 4.44
Vapour Pressure 0.0±2.6 mmHg at 25°C
Index of Refraction 1.569
Storage condition 2-8C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NZ8176000
CHEMICAL NAME :
Kaur-16-en-18-oic acid, 13-hydroxy-
CAS REGISTRY NUMBER :
471-80-7
LAST UPDATED :
199410
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H30-O3
MOLECULAR WEIGHT :
318.50

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
10 gm/L
REFERENCE :
PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 82,2478,1985

 Safety Information

RIDADR NONH for all modes of transport
RTECS NZ8176000

 Precursor & DownStream

Precursor  0

DownStream  2

 Articles42

More Articles
High-performance thin-layer chromatography analysis of steviol glycosides in Stevia formulations and sugar-free food products, and benchmarking with (ultra) high-performance liquid chromatography.

J. Chromatogr. A. 1350 , 102-11, (2014)

A high-performance TLC (HPTLC) method was newly developed and validated for analysis of 7 steviol glycosides in 6 different types of food and Stevia formulations. After a minimized one-step sample pre...

Preparation and chromatographic evaluation of a newly designed steviol glycoside modified-silica stationary phase in hydrophilic interaction liquid chromatography and reversed phase liquid chromatography.

J. Chromatogr. A. 1388 , 110-8, (2015)

A diterpene glycoside compound, rebaudioside A (commonly abbreviated as RA), was immobilized onto porous silica surface through "thiol-ene" click chemistry strategy. The successful immobilization of t...

Determination of eight artificial sweeteners and common Stevia rebaudiana glycosides in non-alcoholic and alcoholic beverages by reversed-phase liquid chromatography coupled with tandem mass spectrometry.

Anal. Bioanal. Chem 407(5) , 1505-12, (2015)

The method for the determination of acesulfame-K, saccharine, cyclamate, aspartame, sucralose, alitame, neohesperidin dihydrochalcone, neotame and five common steviol glycosides (rebaudioside A, rebau...

 Synonyms

steviol
(5β,8α,9β,10α,13α)-13-Hydroxykaur-16-en-18-oic acid
Stevioside
Hydroxydehydrostevic acid
Steviol hydrate
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