Aristolochic acid B

Modify Date: 2025-08-23 23:16:22

Aristolochic acid B structure	Common Name	Aristolochic acid B
	CAS Number	475-80-9	Molecular Weight	311.246
	Density	1.6±0.1 g/cm3	Boiling Point	592.2±50.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₉NO₆	Melting Point	270-272℃
	MSDS	Chinese USA	Flash Point	311.9±30.1 °C

Use of Aristolochic acid B

Aristolochic acid B is one of the major components of Aristolochic acids (AA) which are natural products derived from taxa in the Aristolochiaceae. Aristolochic acid is known to be a potent mutagen and carcinogen. Aristolochic acid B showes more carcinogenic risk than Aristolochic acid A in vivo[1].

Name	Aristolochic acid B
Synonym	More Synonyms

Description	Aristolochic acid B is one of the major components of Aristolochic acids (AA) which are natural products derived from taxa in the Aristolochiaceae. Aristolochic acid is known to be a potent mutagen and carcinogen. Aristolochic acid B showes more carcinogenic risk than Aristolochic acid A in vivo[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Xing G, et al. Comparison of the mutagenicity of aristolochic acid I and aristolochic acid II in the gpt delta transgenic mouse kidney. Mutat Res. 2012 Mar 18;743(1-2):52-8.

Density	1.6±0.1 g/cm3
Boiling Point	592.2±50.0 °C at 760 mmHg
Melting Point	270-272℃
Molecular Formula	C₁₆H₉NO₆
Molecular Weight	311.246
Flash Point	311.9±30.1 °C
Exact Mass	311.042999
PSA	101.58000
LogP	3.50
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.787

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SF8281600

CHEMICAL NAME :: Phenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid, 6-nitro-

CAS REGISTRY NUMBER :: 475-80-9

BEILSTEIN REFERENCE NO. :: 0329754

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C16-H9-N-O6

MOLECULAR WEIGHT :: 311.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: DNA adduct

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 128 ug/kg

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10,275,1987