5-chloro-1-[3-(dimethylamino)propyl]-3-phenylbenzimidazol-2-one

DATA ITEMS CITED :

6

MOLECULAR FORMULA :

C18-H20-Cl-N3-O

MOLECULAR WEIGHT :

329.86

WISWESSER LINE NOTATION :

T6MTJ DXQR&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

142 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

77 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

715 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

90 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

505 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

INPHB6 International Pharmacopsychiatry. (Basel, Switzerland) V.1-17, 1968-72. Volume(issue)/page/year: 1,214,1968