(7α)-9,10-Dimethoxy-1-methyllycorenan-7-ol

Modify Date: 2024-01-07 13:26:38

(7α)-9,10-Dimethoxy-1-methyllycorenan-7-ol Structure
(7α)-9,10-Dimethoxy-1-methyllycorenan-7-ol structure
Common Name (7α)-9,10-Dimethoxy-1-methyllycorenan-7-ol
CAS Number 477-19-0 Molecular Weight 317.379
Density 1.3±0.1 g/cm3 Boiling Point 477.7±45.0 °C at 760 mmHg
Molecular Formula C18H23NO4 Melting Point 199-200ºC
MSDS N/A Flash Point 242.7±28.7 °C

 Use of (7α)-9,10-Dimethoxy-1-methyllycorenan-7-ol


Lycorenine is an alkaloid that has vasodepressor action. Lycorenine also exhibits anticancer and antibacterial activities[1][2][3].

 Names

Name lycorenine
Synonym More Synonyms

  Biological Activity

Description Lycorenine is an alkaloid that has vasodepressor action. Lycorenine also exhibits anticancer and antibacterial activities[1][2][3].
Related Catalog
In Vitro Lycorenine inhibits the cell viability, with IC50s of 0.8 and 1.2 μg/mL for LMTK and HEPG2 cells, respectively[2].
In Vivo Lycorenine (1-10 mg/kg i.v.) produces dose-related decreases in blood pressure and heart rate in anesthetized rats[1].
References

[1]. Miyasaka K, et, al. Pharmacological studies of lycorenine, an alkaloid of Lycoris radiata Herb.: Vasodepressor mechanism in rats. Jpn J Pharmacol. 1979 Aug;29(4):605-22.

[2]. Weniger B, et, al. Cytotoxic activity of Amaryllidaceae alkaloids. Planta Med. 1995 Feb;61(1):77-9.

[3]. Gu D, et, al. Antibacterial Phytosterols and Alkaloids from Lycoris radiate. Natural Product Sciences. 2014 Jou; 20(2): 107-112.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 477.7±45.0 °C at 760 mmHg
Melting Point 199-200ºC
Molecular Formula C18H23NO4
Molecular Weight 317.379
Flash Point 242.7±28.7 °C
Exact Mass 317.162720
PSA 51.16000
LogP 2.39
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.617
Storage condition 2-8°C

 Synonyms

[2]Benzopyrano[3,4-g]indol-7-ol, 1,2,3,5,5a,7,11b,11c-octahydro-9,10-dimethoxy-1-methyl-, (5aR,7S,11bS,11cS)-
ycorenine
(7α)-9,10-Dimethoxy-1-methyllycorenan-7-ol