(7α)-9,10-Dimethoxy-1-methyllycorenan-7-ol

Modify Date: 2025-08-29 18:13:35

(7α)-9,10-Dimethoxy-1-methyllycorenan-7-ol structure	Common Name	(7α)-9,10-Dimethoxy-1-methyllycorenan-7-ol
	CAS Number	477-19-0	Molecular Weight	317.379
	Density	1.3±0.1 g/cm3	Boiling Point	477.7±45.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₂₃NO₄	Melting Point	199-200ºC
	MSDS	N/A	Flash Point	242.7±28.7 °C

Use of (7α)-9,10-Dimethoxy-1-methyllycorenan-7-ol

Lycorenine is an alkaloid that has vasodepressor action. Lycorenine also exhibits anticancer and antibacterial activities[1][2][3].

Name	lycorenine
Synonym	More Synonyms

Description	Lycorenine is an alkaloid that has vasodepressor action. Lycorenine also exhibits anticancer and antibacterial activities[1][2][3].
Related Catalog	Research Areas >> Cancer Research Areas >> Cardiovascular Disease Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Lycorenine inhibits the cell viability, with IC50s of 0.8 and 1.2 μg/mL for LMTK and HEPG2 cells, respectively[2].
In Vivo	Lycorenine (1-10 mg/kg i.v.) produces dose-related decreases in blood pressure and heart rate in anesthetized rats[1].
References	[1]. Miyasaka K, et, al. Pharmacological studies of lycorenine, an alkaloid of Lycoris radiata Herb.: Vasodepressor mechanism in rats. Jpn J Pharmacol. 1979 Aug;29(4):605-22. [2]. Weniger B, et, al. Cytotoxic activity of Amaryllidaceae alkaloids. Planta Med. 1995 Feb;61(1):77-9. [3]. Gu D, et, al. Antibacterial Phytosterols and Alkaloids from Lycoris radiate. Natural Product Sciences. 2014 Jou; 20(2): 107-112.

Density	1.3±0.1 g/cm3
Boiling Point	477.7±45.0 °C at 760 mmHg
Melting Point	199-200ºC
Molecular Formula	C₁₈H₂₃NO₄
Molecular Weight	317.379
Flash Point	242.7±28.7 °C
Exact Mass	317.162720
PSA	51.16000
LogP	2.39
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.617
InChIKey	VHYYSQODIQWPDO-PILAGYSTSA-N
SMILES	COc1cc2c(cc1OC)C1C(CC=C3CCN(C)C31)OC2O
Storage condition	2-8°C

Name: Antibacterial activity against Escherichia coli assessed as diameter of inhibition zo...
Source: ChEMBL
Target: Escherichia coli
External Id: CHEMBL4180035

Name: Antibacterial activity against Staphylococcus aureus assessed as diameter of inhibiti...
Source: ChEMBL
Target: Staphylococcus aureus
External Id: CHEMBL4180036

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ycorenine

(7α)-9,10-Dimethoxy-1-methyllycorenan-7-ol