1H-Pyrido[3,4-b]indole,2,3,4,9-tetrahydro-7-methoxy-1-methyl- (9CI)
![1H-Pyrido[3,4-b]indole,2,3,4,9-tetrahydro-7-methoxy-1-methyl- (9CI) Structure](https://image.chemsrc.com/caspic/429/486-93-1.png)
1H-Pyrido[3,4-b]indole,2,3,4,9-tetrahydro-7-methoxy-1-methyl- (9CI) structure
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Common Name | 1H-Pyrido[3,4-b]indole,2,3,4,9-tetrahydro-7-methoxy-1-methyl- (9CI) | ||
|---|---|---|---|---|
| CAS Number | 486-93-1 | Molecular Weight | 216.27900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H16N2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | Leptaflorine |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C13H16N2O |
|---|---|
| Molecular Weight | 216.27900 |
| Exact Mass | 216.12600 |
| PSA | 37.05000 |
| LogP | 2.71200 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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~99%
1H-Pyrido[3,4-b... CAS#:486-93-1 |
| Literature: Barbaro, Pierluigi; Gonsalvi, Luca; Guerriero, Antonella; Liguori, Francesca Green Chemistry, 2012 , vol. 14, # 11 p. 3211 - 3219 |
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~98%
1H-Pyrido[3,4-b... CAS#:486-93-1 |
| Literature: Schonenberger; Brossi Helvetica Chimica Acta, 1986 , vol. 69, # 6 p. 1486 - 1497 |
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~79%
1H-Pyrido[3,4-b... CAS#:486-93-1 |
| Literature: Song, Hongjian; Liu, Yongxian; Liu, Yuxiu; Wang, Lizhong; Wang, Qingmin Journal of Agricultural and Food Chemistry, 2014 , vol. 62, # 5 p. 1010 - 1018 |
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~61%
1H-Pyrido[3,4-b... CAS#:486-93-1 |
| Literature: Wu, Jianjun; Talwar, Dinesh; Johnston, Steven; Yan, Ming; Xiao, Jianliang Angewandte Chemie - International Edition, 2013 , vol. 52, # 27 p. 6983 - 6987 Ross. Khim. Zh., 2013 , vol. 125, # 27 p. 7121 - 7125,5 |
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~%
1H-Pyrido[3,4-b... CAS#:486-93-1 |
| Literature: Fischer,O. Chemische Berichte, 1889 , vol. 22, p. 638 Chemische Berichte, 1897 , vol. 30, p. 2484 |
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~%
1H-Pyrido[3,4-b... CAS#:486-93-1 |
| Literature: Akabori; Saito Chemische Berichte, 1930 , vol. 63, p. 2245,2247 |
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~%
1H-Pyrido[3,4-b... CAS#:486-93-1 |
| Literature: Akabori; Saito Chemische Berichte, 1930 , vol. 63, p. 2245,2247 |
![2-benzyl-7-methoxy-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole structure](https://image.chemsrc.com/caspic/233/57032-15-2.png)
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 8 | |
|---|---|
| DownStream 2 | |
![1-(7-methoxy-1-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl)ethanone structure](https://image.chemsrc.com/caspic/313/17952-72-6.png)
CAS#:17952-72-6This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
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Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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Name: Displacement of [3H]flunitrazepam from GABAA (unknown origin ) receptor by radioligan...
Source: ChEMBL
Target: Gamma-aminobutyric acid receptor subunit gamma-2
External Id: CHEMBL5235566
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| Tetrahydroharmin |
| tetrahydroharmane |
| 1,2,3,4-Tetrahydroharmine |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the Chinese name of 486-93-1? |
| A: Chinese name of 486-93-1 is 486-93-1. |
| Q: What are the upstream materials of Leptaflorine? |
| A: Related upstream materials(CAS) of Leptaflorine: 304-21-2;6027-98-1;57032-15-2;75-07-0;3610-36-4;442-51-3;3189-13-7;23084-35-7. |
| Q: What is the polar surface area (PSA) of Leptaflorine? |
| A: Polar surface area (PSA) of Leptaflorine is 37.05000. |
| Q: What is the CAS number of Leptaflorine? |
| A: CAS number of Leptaflorine is 486-93-1. |
| Q: What English synonyms does Leptaflorine have? |
| A: English synonyms of Leptaflorine: Tetrahydroharmin, tetrahydroharmane, 1,2,3,4-Tetrahydroharmine. |
| Q: What is the molecular formula of Leptaflorine? |
| A: Molecular formula of Leptaflorine is C13H16N2O. |
| Q: What is the English name of Leptaflorine? |
| A: The English name of Leptaflorine is Leptaflorine. |
| Q: What are the downstream products of Leptaflorine? |
| A: Related downstream products(CAS) of Leptaflorine: 442-51-3;17952-72-6. |
| Q: What is the molecular weight of Leptaflorine? |
| A: Molecular weight of Leptaflorine is 216.27900. |
| Q: What is the LogP of Leptaflorine? |
| A: LogP of Leptaflorine is 2.71200. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Dayang Chem (Hangzhou) Co., Ltd. |