Amiphenazole

Modify Date: 2026-07-01 18:50:49

Amiphenazole Structure
Amiphenazole structure
Common Name Amiphenazole
CAS Number 490-55-1 Molecular Weight 191.25300
Density 1.347g/cm3 Boiling Point 413.3ºC at 760mmHg
Molecular Formula C9H9N3S Melting Point N/A
MSDS N/A Flash Point 203.7ºC

Summary: Amiphenazole (5-phenyl-1,3-thiazole-2,4-diamine, CAS: 490-55-1), molecular formula C9H9N3S, molecular weight 191.25300, density 1.347g/cm3, boiling point 413.3°C. For research-use only, not for medical or clinical usage.


 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 5-phenyl-1,3-thiazole-2,4-diamine
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.347g/cm3
Boiling Point 413.3ºC at 760mmHg
Molecular Formula C9H9N3S
Molecular Weight 191.25300
Flash Point 203.7ºC
Exact Mass 191.05200
PSA 93.17000
LogP 3.13690
Vapour Pressure 4.86E-07mmHg at 25°C
Index of Refraction 1.715
InChIKey UPOYFZYFGWBUKL-UHFFFAOYSA-N
SMILES Nc1nc(N)c(-c2ccccc2)s1

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ4020000
CHEMICAL NAME :
Thiazole, 2,4-diamino-5-phenyl-
CAS REGISTRY NUMBER :
490-55-1
BEILSTEIN REFERENCE NO. :
0157088
LAST UPDATED :
199706
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H9-N3-S
MOLECULAR WEIGHT :
191.27
WISWESSER LINE NOTATION :
T5N CSJ BZ DR& EZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,1125,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
290 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory obstruction Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 7,489,1973

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

HS Code 2934100090

 Synthetic Route

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

~%

Amiphenazole Structure

Amiphenazole

CAS#:490-55-1

Learn More
Literature: Dodson; Turner Journal of the American Chemical Society, 1951 , vol. 73, p. 4517

~%

Amiphenazole Structure

Amiphenazole

CAS#:490-55-1

Learn More
Literature: Chase; Walker Journal of the Chemical Society, 1955 , p. 4443,4450

~%

Amiphenazole Structure

Amiphenazole

CAS#:490-55-1

Learn More
Literature: Davies et al. Journal of the Chemical Society, 1950 , p. 3491,3494

~%

Amiphenazole Structure

Amiphenazole

CAS#:490-55-1

Learn More
Literature: Miryan,N.I. et al. Pharmaceutical Chemistry Journal, 1973 , vol. 7, # 8 p. 489 - 491 Khimiko-Farmatsevticheskii Zhurnal, 1973 , vol. 7, # 8 p. 17 - 20

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  4

DownStream  0

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 AmiphenazoleBioassay

View more

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase
Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344
Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233
Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898
Total 265, Current Page 1 of 27
1
2
3
4
5

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

5-phenyl-thiazole-2,4-diyldiamine
Fenamizol
Dizol
Phenamizol
2,4-diamino-5-phenylthiazole
Amiphenazole
Daptazile
5-phenyl-thiazole-2,4-diamine
Amifenazol
Phenamizole
Amiphenazol
Daftazol
5-Phenyl-thiazol-2,4-diyldiamin

 Amiphenazole | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the English name of 5-phenyl-1,3-thiazole-2,4-diamine?
A: The English name of 5-phenyl-1,3-thiazole-2,4-diamine is 5-phenyl-1,3-thiazole-2,4-diamine.
Q: What is the polar surface area (PSA) of 5-phenyl-1,3-thiazole-2,4-diamine?
A: Polar surface area (PSA) of 5-phenyl-1,3-thiazole-2,4-diamine is 93.17000.
Q: What is the molecular weight of 5-phenyl-1,3-thiazole-2,4-diamine?
A: Molecular weight of 5-phenyl-1,3-thiazole-2,4-diamine is 191.25300.
Q: What is the molecular formula of 5-phenyl-1,3-thiazole-2,4-diamine?
A: Molecular formula of 5-phenyl-1,3-thiazole-2,4-diamine is C9H9N3S.
Q: What is the SMILES notation of 5-phenyl-1,3-thiazole-2,4-diamine?
A: SMILES notation of 5-phenyl-1,3-thiazole-2,4-diamine is Nc1nc(N)c(-c2ccccc2)s1.
Q: What is the LogP of 5-phenyl-1,3-thiazole-2,4-diamine?
A: LogP of 5-phenyl-1,3-thiazole-2,4-diamine is 3.13690.
Q: What English synonyms does 5-phenyl-1,3-thiazole-2,4-diamine have?
A: English synonyms of 5-phenyl-1,3-thiazole-2,4-diamine: 5-phenyl-thiazole-2,4-diyldiamine, Fenamizol, Dizol, Phenamizol, 2,4-diamino-5-phenylthiazole, Amiphenazole, Daptazile, 5-phenyl-thiazole-2,4-diamine, Amifenazol, Phenamizole, Amiphenazol, Daftazol, 5-Phenyl-thiazol-2,4-diyldiamin.
Q: What is the boiling point of 5-phenyl-1,3-thiazole-2,4-diamine?
A: Boiling point of 5-phenyl-1,3-thiazole-2,4-diamine is 413.3ºC at 760mmHg.
Q: What is the InChIKey of 5-phenyl-1,3-thiazole-2,4-diamine?
A: InChIKey of 5-phenyl-1,3-thiazole-2,4-diamine is UPOYFZYFGWBUKL-UHFFFAOYSA-N.
Q: What is the CAS number of 5-phenyl-1,3-thiazole-2,4-diamine?
A: CAS number of 5-phenyl-1,3-thiazole-2,4-diamine is 490-55-1.
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.