2-Amino-6-methylthiopurine ribonucleoside

Modify Date: 2024-01-29 19:06:38

2-Amino-6-methylthiopurine ribonucleoside Structure
2-Amino-6-methylthiopurine ribonucleoside structure
Common Name 2-Amino-6-methylthiopurine ribonucleoside
CAS Number 4914-73-2 Molecular Weight 299.31
Density 1.98g/cm3 Boiling Point 743.6ºC at 760 mmHg
Molecular Formula C10H13N5O4S Melting Point N/A
MSDS N/A Flash Point 403.5ºC

 Use of 2-Amino-6-methylthiopurine ribonucleoside


2-Amino-6-meThythio-9-(β-D-ribofuranosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-(2-amino-6-methylsulfanylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Synonym More Synonyms

  Biological Activity

Description 2-Amino-6-meThythio-9-(β-D-ribofuranosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.98g/cm3
Boiling Point 743.6ºC at 760 mmHg
Molecular Formula C10H13N5O4S
Molecular Weight 299.31
Flash Point 403.5ºC
Exact Mass 313.08400
PSA 164.84000
Index of Refraction 1.878

 Synonyms

S-methylthioguanosine
(2R,3R,4S,5R)-2-[2-amino-6-(methylthio)-9H-purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
PC 250
S-methyl-6-thio-guanosine
HMS3078N18
6-(methylsulfanyl)-9-pentofuranosyl-9h-purin-2-amine