TB-03

Modify Date: 2024-01-19 18:08:24

TB-03 Structure
TB-03 structure
Common Name TB-03
CAS Number 491831-49-3 Molecular Weight 708.73800
Density N/A Boiling Point N/A
Molecular Formula C36H45N4O9P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TB-03


A small molecule Grb2 SH2 domain binding antagonist that synergistically enhances inhibition of K562 leukemia cell proliferation by imatinib (CI=0.774).

 Names

Name (3R)-4-[[1-[[(2S)-4-amino-1-(3-naphthalen-1-ylpropylamino)-1,4-dioxobutan-2-yl]carbamoyl]cyclohexyl]amino]-4-oxo-3-[[4-(phosphonomethyl)phenyl]methyl]butanoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C36H45N4O9P
Molecular Weight 708.73800
Exact Mass 708.29200
PSA 235.03000
LogP 4.95220

 Synonyms

TB-03
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