3-(chloromethyl)-5-(3-fluorophenyl)-1,2,4-oxadiazole

Modify Date: 2024-01-11 20:22:09

3-(chloromethyl)-5-(3-fluorophenyl)-1,2,4-oxadiazole Structure
3-(chloromethyl)-5-(3-fluorophenyl)-1,2,4-oxadiazole structure
Common Name 3-(chloromethyl)-5-(3-fluorophenyl)-1,2,4-oxadiazole
CAS Number 491842-63-8 Molecular Weight 212.60800
Density 1.364g/cm3 Boiling Point 321.778ºC at 760 mmHg
Molecular Formula C9H6ClFN2O Melting Point N/A
MSDS N/A Flash Point 148.406ºC

 Names

Name 3-(chloromethyl)-5-(3-fluorophenyl)-1,2,4-oxadiazole

 Chemical & Physical Properties

Density 1.364g/cm3
Boiling Point 321.778ºC at 760 mmHg
Molecular Formula C9H6ClFN2O
Molecular Weight 212.60800
Flash Point 148.406ºC
Exact Mass 212.01500
PSA 38.92000
LogP 2.61450
Index of Refraction 1.542

 Safety Information

HS Code 2934999090

 Synthetic Route

~35%

3-(chloromethyl)-5-(3-fluorophenyl)-1,2,4-oxadiazole Structure

3-(chloromethyl...

CAS#:491842-63-8

Literature: ASTRA ZENECA AB; NPS PHARMACEUTICALS, INC. Patent: WO2004/14881 A2, 2004 ; Location in patent: Page 105 ; WO 2004/014881 A2

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3-(chloromethyl)-5-(3-fluorophenyl)-1,2,4-oxadiazole Structure

3-(chloromethyl...

CAS#:491842-63-8

Literature: Zablocki, Jeff; Kalla, Rao; Perry, Thao; Palle, Venkata; Varkhedkar, Vaibhav; Xiao, Dengming; Piscopio, Anthony; Maa, Tenning; Gimbel, Art; Hao, Jia; Chu, Nancy; Leung, Kwan; Zeng, Dewan Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 3 p. 609 - 612 Title/Abstract Full Text View citing articles Show Details Elzein, Elfatih; Ibrahim, Prabha; Koltun, Dmitry O.; Rehder, Ken; Shenk, Kevin D.; Marquart, Timothy A.; Jiang, Bob; Li, Xiaofen; Natero, Reina; Li, Yuan; Nguyen, Marie; Kerwar, Suresh; Chu, Nancy; Soohoo, Daniel; Hao, Jia; Maydanik, Victoria Y.; Lustig, David A.; Zeng, Dewan; Leung, Kwan; Zablocki, Jeff A. Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 24 p. 6017 - 6021

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3-(chloromethyl)-5-(3-fluorophenyl)-1,2,4-oxadiazole Structure

3-(chloromethyl...

CAS#:491842-63-8

Literature: Lankau, Hans-Joachim; Unverferth, Klaus; Grunwald, Christian; Hartenhauer, Helge; Heinecke, Kristina; Bernoester, Katrin; Dost, Rita; Egerland, Ute; Rundfeldt, Chris European Journal of Medicinal Chemistry, 2007 , vol. 42, # 6 p. 873 - 879

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3-(chloromethyl)-5-(3-fluorophenyl)-1,2,4-oxadiazole Structure

3-(chloromethyl...

CAS#:491842-63-8

Literature: Elzein, Elfatih; Ibrahim, Prabha; Koltun, Dmitry O.; Rehder, Ken; Shenk, Kevin D.; Marquart, Timothy A.; Jiang, Bob; Li, Xiaofen; Natero, Reina; Li, Yuan; Nguyen, Marie; Kerwar, Suresh; Chu, Nancy; Soohoo, Daniel; Hao, Jia; Maydanik, Victoria Y.; Lustig, David A.; Zeng, Dewan; Leung, Kwan; Zablocki, Jeff A. Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 24 p. 6017 - 6021

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%