Ethyl (5Z,9Z,12Z)-5,9,12-octadecatrienoate

Modify Date: 2024-02-01 17:36:13

Ethyl (5Z,9Z,12Z)-5,9,12-octadecatrienoate Structure
Ethyl (5Z,9Z,12Z)-5,9,12-octadecatrienoate structure
Common Name Ethyl (5Z,9Z,12Z)-5,9,12-octadecatrienoate
CAS Number 493015-74-0 Molecular Weight 306.483
Density 0.9±0.1 g/cm3 Boiling Point 390.6±31.0 °C at 760 mmHg
Molecular Formula C20H34O2 Melting Point N/A
MSDS N/A Flash Point 100.8±23.2 °C

 Use of Ethyl (5Z,9Z,12Z)-5,9,12-octadecatrienoate


Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.

 Names

Name ethyl octadeca-5,9,12-trienoate
Synonym More Synonyms

  Biological Activity

Description Pinolenic acid is a polyunsaturated fatty acid found in the seed oils of red pine (Pinus orientalis) and maritime pine (Pinus pinaster). Both oils were found to have lipid-lowering properties. A diet containing marine pine nut oil (MPSO) reduces HDL and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to reduce cholesterol efflux in vitro. Korean pine nut oil supplements may help obesity by reducing appetite. People who take this oil experience an increase in the satiety hormones CCK and GLP-1 and a decrease in appetite. The activity of the oil is attributed to pinolenic acid. Pinolenic acid is not metabolized to arachidonic acid and can reduce the level of arachidonic acid in the phosphatidylinositol fraction of HepG2 cells from 15.9% to 7.0%. Pinolenic acid ethyl ester is a neutral, more lipophilic form of the free acid.
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 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 390.6±31.0 °C at 760 mmHg
Molecular Formula C20H34O2
Molecular Weight 306.483
Flash Point 100.8±23.2 °C
Exact Mass 306.255890
PSA 26.30000
LogP 7.65
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.475

 Synonyms

Ethyl (5Z,9Z,12Z)-5,9,12-octadecatrienoate
ethyl 5Z,9Z,12Z-octadecatrienoate
5,9,12-Octadecatrienoic acid, ethyl ester, (5Z,9Z,12Z)-
ethyl pinolenate
pinolenic acid ethyl ester