Smilagenin acetate

Modify Date: 2025-09-29 18:21:13

Smilagenin acetate Structure
Smilagenin acetate structure
Common Name Smilagenin acetate
CAS Number 4947-75-5 Molecular Weight 458.67300
Density 1.11g/cm3 Boiling Point 527.5ºC at 760mmHg
Molecular Formula C29H46O4 Melting Point N/A
MSDS N/A Flash Point 221.8ºC

 Use of Smilagenin acetate


Smilagenin acetate is a Sapogenin derivative extracted from patent US20030004147A1. Smilagenin acetate increases the expression of acetylcholine m2 receptors and can be used for the research of dementia[1].

 Names

Name smilagenin, acetate
Synonym More Synonyms

 Smilagenin acetate Biological Activity

Description Smilagenin acetate is a Sapogenin derivative extracted from patent US20030004147A1. Smilagenin acetate increases the expression of acetylcholine m2 receptors and can be used for the research of dementia[1].
Related Catalog
In Vitro Smilagenin acetate increases the expression of m2 receptors on CHO cells transfected with DNA for the m2 receptor[1].
References

[1]. Paul Barraclough, et al. 5-beta-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia. US20030004147A1.

 Chemical & Physical Properties

Density 1.11g/cm3
Boiling Point 527.5ºC at 760mmHg
Molecular Formula C29H46O4
Molecular Weight 458.67300
Flash Point 221.8ºC
Exact Mass 458.34000
PSA 44.76000
LogP 6.36460
InChIKey LVRAKYNQYKVPIK-BSPYNPCNSA-N
SMILES CC(=O)OC1CCC2(C)C(CCC3C2CCC2(C)C3CC3OC4(CCC(C)CO4)C(C)C32)C1
Storage condition 2-8℃

 Smilagenin acetateBioassay

View more

Name: Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimo...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 1B1
External Id: CHEMBL3039488
Name: ERK5 transcriptional activity HTS
Source: 24565
Target: N/A
External Id: ERK5 transcriptional activity-HTS
Name: NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell L...
Source: DTP/NCI
Target: N/A
External Id: MCF7_OneDose
Name: NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell...
Source: DTP/NCI
Target: N/A
External Id: IGROV1_OneDose
Name: Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimo...
Source: ChEMBL
Target: Solute carrier organic anion transporter family member 1B3
External Id: CHEMBL3039491
Name: HIV Cellular Data
Source: NIAID
Target: N/A
External Id: HIV Cellular Data
Name: Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening
Source: 11827
Target: Phosphogluconate dehydrogenase
External Id: 6PGD_Inhibitor_Screening_2015_09
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 Synonyms

25R,5BETA-SPIROSTAN-3BETA-OL 3-ACETATE
3-O-acetylsarsasapogenin
Smilagenin Acetate
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