3-deoxyvasicine structure
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Common Name | 3-deoxyvasicine | ||
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CAS Number | 495-59-0 | Molecular Weight | 172.22600 | |
Density | 1.23g/cm3 | Boiling Point | 311.6ºC at 760mmHg | |
Molecular Formula | C11H12N2 | Melting Point | 96.5-97.5 °C | |
MSDS | N/A | Flash Point | 142.3ºC |
Use of 3-deoxyvasicineDesoxypeganine (Deoxypeganine), an alkaloid, is a potent and orally active cholinesterase (BChE and AChE) and selective MAO-A inhibitor, with IC50 values of 2, 17, and 2 μM, respectively. Desoxypeganine can be used for alcohol abuse research[1]. |
Name | 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline |
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Synonym | More Synonyms |
Description | Desoxypeganine (Deoxypeganine), an alkaloid, is a potent and orally active cholinesterase (BChE and AChE) and selective MAO-A inhibitor, with IC50 values of 2, 17, and 2 μM, respectively. Desoxypeganine can be used for alcohol abuse research[1]. |
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Related Catalog | |
Target |
BChE:2 μM (IC50) AChE:17 μM (IC50) MAO-A:2 μM (IC50) |
In Vivo | Desoxypeganine (10-30 mg/kg,灌胃,每天一次,连续 16 天) 剂量依赖性地降低乙醇摄入量和乙醇偏好[1]。 Animal Model: Female Alko alcohol (AA) rats (Thirty eight adult)[1] Dosage: 10, 20, 30 mg/kg Administration: Gavage, once daily in a volume of 10 ml/kg at 6:00 pm, for 16 days Result: Abolished ethanol preference. |
References |
Density | 1.23g/cm3 |
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Boiling Point | 311.6ºC at 760mmHg |
Melting Point | 96.5-97.5 °C |
Molecular Formula | C11H12N2 |
Molecular Weight | 172.22600 |
Flash Point | 142.3ºC |
Exact Mass | 172.10000 |
PSA | 15.60000 |
LogP | 1.69950 |
Precursor 9 | |
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DownStream 8 | |
2,3-trimethylene-3,4-dihydroquinazoline |
deoxypeganine |
3-deoxyvasicine |
Deoxypeganin |
Desoxypeganine |
deoxyvasicine |
3-Deoxypeganine |
deoxypeganol |