5-Methyl-4-thiouridine

Modify Date: 2024-01-12 10:38:59

5-Methyl-4-thiouridine Structure
5-Methyl-4-thiouridine structure
Common Name 5-Methyl-4-thiouridine
CAS Number 49555-43-3 Molecular Weight 274.29
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H14N2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5-Methyl-4-thiouridine


5-Methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-Methyl-1-(β-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
Synonym More Synonyms

 5-Methyl-4-thiouridine Biological Activity

Description 5-Methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C10H14N2O5S
Molecular Weight 274.29
Exact Mass 274.062347
LogP 0.38
Index of Refraction 1.703

 Synonyms

5-Methyl-1-(β-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
2(1H)-Pyrimidinone, 3,4-dihydro-5-methyl-1-β-D-ribofuranosyl-4-thioxo-
Top Suppliers:I want be here

No recommended suppliers.

Hot Compounds More...
Dichloromethane
CAS#:75-09-2
Polyacrylic acid
CAS#:9003-01-4
sodium carbonate
CAS#:497-19-8
Silicon dioxide
CAS#:7631-86-9
Triethanolamine
CAS#:102-71-6
Demeton
CAS#:126-75-0
Water
CAS#:7732-18-5
4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9
Diclofenac sodium
CAS#:15307-79-6
Budesonide
CAS#:51372-29-3