5-Methyl-4-thiouridine

Modify Date: 2024-01-12 10:38:59

5-Methyl-4-thiouridine structure	Common Name	5-Methyl-4-thiouridine
	CAS Number	49555-43-3	Molecular Weight	274.29
	Density	1.6±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₄N₂O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 5-Methyl-4-thiouridine

5-Methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5-Methyl-1-(β-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
Synonym	More Synonyms

Description	5-Methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.6±0.1 g/cm3
Molecular Formula	C₁₀H₁₄N₂O₅S
Molecular Weight	274.29
Exact Mass	274.062347
LogP	0.38
Index of Refraction	1.703

5-Methyl-1-(β-D-ribofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone

2(1H)-Pyrimidinone, 3,4-dihydro-5-methyl-1-β-D-ribofuranosyl-4-thioxo-

5-Methyl-4-thiouridine

Use of 5-Methyl-4-thiouridine

Names

5-Methyl-4-thiouridine Biological Activity

Chemical & Physical Properties

Synonyms